Effect of interventional embolectomy with Navien catheter and Solitaire AB stent on vascular recanalization rate,neurological function improvement and prognosis in patients with acute cerebral infarction
Objective:To investigate the effect of interventional embolectomy with Navien catheter and Solitaire AB stent on the vascular recanalization rate,neurological function improvement and prognosis in patients with acute cerebral infarction(ACI).Methods:One hundred and thirty-four patients with ACI who lost the chance of thrombolysis admitted to our hospital from June 2018 to January 2022 were selected for for retrospective analysis.According to different surgical schemes,all patients were divided into stent thrombectomy group and combined thrombectomy group,with 67 cases in each group.Stent interventional thrombectomy with Solitaire AB stent was performed in the stent thrombectomy group,and interventional embolectomy with Navien catheter and Solitaire AB stent was performed in the combined thrombectomy group.The vascular recanalization,the number of embolectomy,the levels of neurofunctional factors,the scores of Chinese stroke clinical neurological deficit scale(CSS),activity of daily living scale(ADL)after 1 month of operation,the score of modified Rankin scale(mRS)after 3 months of operation were compared between the two groups.Results:The vascular recanalization rate of the combined thrombectomy group was significantly higher than that of the stent thrombectomy group,and the number of thrombectomy was significantly less than that of the stent thrombectomy group(P<0.05).After 1 month of operation,the levels of neuron specific enolase(NSE)and stellate source sex protein(S100β),CSS score,ADL score in the combined thrombectomy group were significantly lower than those in the stent thrombectomy group,the levels of nerve growth factor(NGF)and brain-derived neurotrophic factor(BDNF)were significantly higher than those in the stent thrombectomy group(P<0.05).After 3 months of operation,the number of patients in the combined embolectomy group with 0 to 2 and 3 points of scores in the prognosis mRS score was significantly higher than that in the stent embolectomy group(P<0.05).The number of people who scored 4-5 and 6 was significantly less than that in the stent embolectomy group(P<0.05).Conclusion:The interventional embolectomy with Navien catheter and Solitaire AB stent in the treatment of ACI patients who have lost the chance of thrombolysis has the advantages of less times of embolectomy,higher rate of vascular recanalization,regulating the levels of nerve function factors,reducing the degree of nerve function injury,improving the daily survival ability and improving the prognosis of patients.
Stent interventional thrombectomyAcute cerebral infarctionNerve function
万方数据
维普
