首页|重症超声监测指导在需行血流动力学监测的ARDS患者中的应用及其对NT-proBNP、心肌酶及A-aDO2 的影响

重症超声监测指导在需行血流动力学监测的ARDS患者中的应用及其对NT-proBNP、心肌酶及A-aDO2 的影响

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目的:探讨重症超声监测指导在需行血流动力学监测的急性呼吸窘迫综合征(Acute respiratory distress syndrome,ARDS)患者中的应用效果.方法:选取 2020 年 7 月至 2022 年 5 月期间我科收治的 103 例进行血流动力学监测的 ARDS 患者作为研究对象,随机分为对照组(n=51)和观察组(n=52).对照组接受脉搏指示连续心排血量监测(Pulse indicator continuous cardiac output,PiCCO)指导,观察组接受重症超声联合PiCCO监测指导.对比两组患者血容量、心功能、氧合情况.结果:治疗3 d后,观察组的下腔静脉呼吸异变率、每搏量(Stroke volume,SV)、中心静脉压(Central venous pressure,CVP)高于对照组,下腔静脉(Inferior Vena Cava,IVC)低于对照组(P<0.05).观察组的血清N末端B型利钠肽原(N-terminal B-type natriuretic peptide,NT-proBNP)、肌酸激酶同工酶(Creatine Kinase-MB,CK-MB)、肌酸激酶(Creatine Kinase,CK)水平低于对照组(P<0.05).观察组的氧合指数高于对照组,肺泡-动脉氧分压差(Alveolar-arterial oxygen partial pressure difference,A-aDO2)低于对照组(P<0.05).观察组的液体入量低于对照组,液体出量高于对照组(P<0.05).结论:重症超声联合PiCCO监测指导用于ARDS容量管理,可更好地改善患者的肺部氧合,在恢复机体正常血容量的基础上减少液体的入量,并促进心功能恢复.
Application of severe ultrasound monitoring guidance in ARDS patients requiring hemodynamic monitoring and its effect on NT-proBNP,myocardial enzymes and A-aDO2
Objective:To investigate the application effect of severe ultrasound monitoring in patients with Acute respiratory distress syndrome(ARDS)requiring hemodynamic monitoring.Methods:A total of 103 ARDS patients admitted to our department from July 2020 to May 2022 for hemodynamic monitoring were selected as research objects,and randomly divided into control group(n=51)and observation group(n=52).The control group received the guidance of Pulse indicator continuous cardiac output(PiCCO),while the observation group received the guidance of intensive ultrasound combined with PiCCO monitoring.Blood volume,cardiac function and oxygenation were compared between the two groups.Results:After 3d treatment,the variation rate of Inferior Vena Cava respiratory,Stroke volume(SV)and Central venous pressure(CVP)in the observation group are higher than those in the control group,and Inferior Vena Cava,IVC was lower than that of control group(P<0.05).Serum N-terminal B-type natriuretic peptide(NT-proBNP),Creatine kinase-MB(CK-MB)and Creatine Kinase(Creatine Kinase)in the observation group.The level of CK was lower than that of control group(P<0.05).The oxygenation index of the observation group was higher than that of the control group,and the Alveolar-arterial oxygen partial pressure difference(A-aDO2)was lower than that of the control group(P<0.05).The liquid intake in the observation group was lower than that in the control group,but the liquid output was higher than that in the control group(P<0.05).Conclusion:Intensive ultrasound combined with PiCCO monitoring guidance for ARDS volume management can better improve lung oxygenation,reduce fluid intake on the basis of restoring normal blood volume,and promote the recovery of cardiac function.

Acute respiratory distress syndromeContinuous cardiac output monitoringBlood volumeCardiac functionRespiratory function

吕雪涵、夏慧芳、米田

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河南科技大学第一附属医院呼吸与危重症医学科,河南 洛阳 471000

急性呼吸窘迫综合征 连续心排血量监测 血容量 心功能 呼吸功能

2024

四川生理科学杂志
四川省生理科学会

四川生理科学杂志

影响因子:0.575
ISSN:1671-3885
年,卷(期):2024.46(1)
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