Effects of supplementation of omega-3 fish oil fat milk on gastrointestinal function in patients with preserved duodeno-pancreaticotomy
Objective:To investigate the effect of omega-3 fish oil fat milk supplemental nutrition support in patients with preserved duodeno-pancreaticotomy.Methods:A total of 104 cases of reserved duodenopancreatic resection from July 2020 to September 2022 in our department were selected and grouped according to the lottery method.Control group 52 cases were given parenteral nutrition support and enteral mixed nutrition support,Observation group 52 cases were given the supplemental nutrition support of ω-3 fish oil fat milk on this basis.After 6 days of intervention,the indexes of postoperative gastrointestinal function recovery were compared between the two groups:postoperative exhaust time,length of hospital stay and time of getting out of bed were observed.Fasting venous blood serum was extracted in the morning,and perioperative nutritional indexes such as Albumin(ALB)and Total Protein(TP)were measured by biuret method,and Hemoglobin(Hb)levels were measured by automatic blood cell analyzer.White blood cell count(WBC)and Lymphocyte count(LY)were tested,Procalcitonin(PCT)was detected by immunochromatography.Interleukin-6(IL-6)levels were measured by enzyme-linked immunosorbent assay to understand perioperative inflammatory responses.Results:There was no statistical significance in the levels of ALB,TP and Hb in 2 groups(P>0.05).The exhaust time,the time to get out of bed and the time to stay in hospital in the observation group were shorter than those in the control group,and the levels of WBC,LY,PCT and IL-6 after intervention were lower than those in the control group(P<0.05).Conclusion:Supplementation of omega-3 fish oil and fat milk with supplemental nutritional support can effectively reduce inflammation and improve nutritional status and gastrointestinal function recovery in patients undergoing duodenopancreatic resection.
Parenteral nutrition supportEnteral nutritional supportOmega-3 fish oil fat milkReserving duodenopancreatectomy
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