首页|沙美特罗替卡松气雾剂辅助治疗老年慢性阻塞性肺疾病呼吸衰竭的疗效观察

沙美特罗替卡松气雾剂辅助治疗老年慢性阻塞性肺疾病呼吸衰竭的疗效观察

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目的:探讨老年慢性阻塞性肺疾病(Chronic Obstructive Pulmonary Disease,COPD)呼吸衰竭患者采取沙美特罗替卡松气雾剂辅助治疗的临床疗效.方法:前瞻性选取 2020 年 8 月至 2022 年 10 月我院接收的 84 例老年COPD呼吸衰竭患者,随机分为两组,各42例.对照组采取无创通气治疗,观察组在对照组基础上采取沙美特罗替卡松气雾剂辅助治疗,两组均治疗 2 w.观察记录两组患者的临床疗效.于治疗前后,采用肺功能检测仪检测两组患者的肺功能相关指标,包括深吸气量(Inspiratory Capacity,IC)、第一秒用力呼气容积(Forced Expiratory Volume In One Second,FEV1)、用力肺活量(Forced Vital Capacity,FVC);于治疗前后,采用COPD患者自我评估测试量表(COPD Assessment Test,CAT)评价两组患者的生活质量.结果:观察组治疗总有效率高于对照组(P<0.05).治疗前,两组FVC、FEV1、IC水平及CAT评分对比无统计学差异(P>0.05);治疗后,观察组FVC、FEV1、IC水平均高于对照组(P<0.05),观察组CAT评分低于对照组(P<0.05).结论:沙美特罗替卡松气雾剂辅助治疗老年COPD呼吸衰竭有助于改善患者的肺功能和生活质量,整体疗效较优,值得推广使用.
Therapeutic effect of Salmeterol and ticasone aerosol in the treatment of respiratory failure in elderly patients with chronic obstructive pulmonary disease
Objective:To investigate the clinical effect of salmeterol and ticasone aerosol in the adjuvant treatment of respiratory failure in elderly patients with Chronic Obstructive Pulmonary Disease(COPD).Methods:84 elderly patients with COPD and respiratory failure admitted to our hospital from August 2020 to October 2022 were prospectively selected and randomly divided into two groups with 42 cases each.The control group was treated with non-invasive ventilation,and the observation group was treated with salmeterol and ticasone aerosol.Both groups were treated for 2 weeks.The clinical effects of the two groups were observed and recorded.Before and after treatment,pulmonary function detector was used to detect the lung function related indexes of the two groups of patients.These include Inspiratory Capacity(IC),Forced Expiratory Volume In One Second(FEV1),and Forced Vital capacity(Forced Vital capacity)Capacity,FVC);Before and after treatment,COPD self-assessment Test(CAT)was used to evaluate the quality of life of patients in both groups.Results:The total effective rate of observation group was higher than that of control group(P<0.05).Before treatment,there were no significant differences in FVC,FEV1,IC level and CAT score between the two groups(P>0.05).After treatment,FVC,FEV1 and IC levels in the observation group were higher than those in the control group(P<0.05),and CAT scores in the observation group were lower than those in the control group(P<0.05).Conclusion:Salmeterol and ticasone aerosol can improve the lung function and quality of life of elderly patients with COPD respiratory failure,and the overall curative effect is good,worthy of promotion.

Elderly chronic obstructive pulmonary diseaseRespiratory failureSalmeterol ticasone aerosolLung function

杨倩、岳婵娟、曾晨悦

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河南省桐柏县人民医院急诊科,河南 南阳 474750

老年慢性阻塞性肺疾病 呼吸衰竭 沙美特罗替卡松气雾剂 肺功能

2024

四川生理科学杂志
四川省生理科学会

四川生理科学杂志

影响因子:0.575
ISSN:1671-3885
年,卷(期):2024.46(1)
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