Clinical efficacy and safety of Qingyi Decoction in the adjuvant treatment of severe acute pancreatitis
Objective:To explore the clinical efficacy and safety of Qingyi Decoction in the adjuvant treatment of severe acute pancreatitis.Methods:76 patients with severe acute pancreatitis admitted to our hospital from July 2020 to July 2022 were selected as the study objects.The patients were randomly divided into study group and control group,38 cases in each group.The control group was treated with ulinastatin.The study group was treated with Qingyi Decoction supplemented with ulinastatin.The data of both groups were observed after 14 days of treatment,and the clinical efficacy,TCM symptom score,pancreatic function improvement time,gastrointestinal function recovery and adverse reactions of the two groups were compared.Results:The total effective rate of the study group was significantly higher than that of the control group(P<0.05).Before treatment,the scores of acute abdominal pain,chest tightness,abdominal distension,nausea,vomiting and loose stool were not significantly different between the two groups.After treatment,the scores of Chinese medicine symptoms in both groups decreased,and the scores of Chinese medicine symptoms in the study group were significantly lower than those in the control group(P<0.05),and the time of urine amylase return to normal and blood amylase return to normal in the study group were significantly shorter than those in the control group(P<0.05).The disappearance time of abdominal pain,fever,intestinal sound recovery time and abdominal distension in the study group were significantly shorter than those in the control group(P<0.05).The adverse reaction rate of the study group was significantly lower than that of the control group(P<0.05).Conclusion:Qingyi Decoction can improve the curative effect,improve the clinical symptoms,promote the recovery of pancreatic function and gastrointestinal function,and reduce the adverse reactions.
Severe acute pancreatitisQingyi DecoctionUlinastatinClinical effectSecurity
NETL
NSTL
万方数据
维普
