Impact of age on blood biochemical indicators in patients with tuberculous pleurisy after anti-tuberculosis treatment
Objective:To investigate the impact of age on blood biochemical indicators in patients with tuberculous pleurisy after anti-tuberculosis treatment.Methods:A total of 142 patients with tuberculous pleurisy admitted to our hospital from May 2019 to May 2022 were selected as the study subjects.According to the World Health Organization(WHO)age classification criteria,the patients are divided into elderly group(n=29,age>59 years),middle-aged group(n=40,44 years<age≤59 years)and young group(n=73,age≤44 years).All groups were given anti-tuberculosis treatment.Therapeutic effects,laboratory indicators and blood biochemical indicators in the three groups were comparatively analyzed.Results:There was no statistically significant difference in therapeutic effects,interferon-γ(INF-γ),or the positive rate of mycobacterium tuberculosis DNA(TB-DNA)among the three groups of pre and post treatment.There was no statistically significant difference in blood biochemical indicators among the three groups before treatment.After treatment,the differences in creatinine(Cr),blood urea nitrogen(BUN),uric acid(UA),total bilirubin(TBIL),total protein(TP)and alanine transaminase(ALT)were statistically significant.The levels of Cr and TP in the middle-aged group were lower than those in the elderly group and the young group.The levels of BUN,UA,TBIL and ALT in elderly and middle-aged groups were lower than those in the young group(P<0.05).Conclusion:The changes in blood biochemical indicators in patients with tuberculous pleurisy after anti-tuberculosis treatment are influenced by age,and the impact on middle-aged and elderly patients is greater than young patients.
NETL
NSTL
万方数据
维普
