Correlation between serum CRP and PCT levels and postoperative anastomotic fistula in patients with colorectal cancer
Objective:To analyze the relationship between the levels of C-reactive protein(CRP)and Procalcitonin(PCT)in serum and the incidence of anastomotic fistula after colorectal cancer surgery.Methods:The clinical data of 60 patients with colorectal cancer admitted from March 2021 to November 2022 were collected,and the incidence of anastomotic fistula was statistically analyzed.According to whether anastomotic fistula occurred,the patients with anastomotic fistula were included in the occurrence group and the non-occurrence group.The serum CRP and PCT levels of the two groups were analyzed and compared,and the relationship between the serum CRP and PCT levels and the incidence of postoperative anastomotic fistula in colorectal cancer patients was analyzed.Results:The levels of serum PCT and CRP in the occurrence group were significantly higher than those in the non-occurrence group(P<0.05).After multiple Logistic regression analysis,serum PCT(β=0.859,OR=2.360,95%CI 1.103-5.050),CRP(β=5.781,OR=324.079,95%CI 2.573-40811.649)was associated with postoperative anastomotic fistula in colorectal cancer patients(P<0.05).Receiver operating curve(ROC)showed that serum PCT and CRP levels alone and in combination predicted the incidence of postoperative anastomotic fistula in colorectal cancer patients:the area under the curve(AUC)was>0.7.Conclusion:High levels of serum CRP and PCT are associated with postoperative anastomotic fistula in patients with colorectal cancer.
colorectal cancerAnastomotic fistulaC-reactive proteinProcalcitoninPredictive value
NETL
NSTL
万方数据
维普
