Relationship between the expression of ALB and FIB before operation and skin flap inactivation in patients with soft tissue defect after skin flap repair
Objective:To investigate the relationship between the expression of Albumin(ALB)and Fibrinogen(FIB)and skin flap inactivation after skin flap repair in patients with soft tissue defect after hand injury.Methods:A total of 96 patients with hand injury and soft tissue defect admitted to our hospital from January 2020 to December 2022 were selected as the observation group,and 97 healthy subjects were selected as the healthy control group.The levels of ALB and FIB in observation group and healthy control group were analyzed and compared.All the patients were treated with pedicled skin flap repair.The survival of the skin flap after operation was analyzed and divided into survival group and inactivation group according to the survival of the skin flap after operation.The levels of ALB and FIB were analyzed and compared between the flap survival group and the flap inactivation group,and the relationship between the expression of ALB and FIB and the flap inactivation after the flap repair was examined by point two-column correlation analysis.Results:The level of ALB in observation group was lower than that in healthy control group,and the level of FIB was higher than that in healthy control group(P<0.05).In the observation group,14 cases of postoperative flap inactivation occurred,accounting for 14.58%.The level of ALB in deactivated flap group was lower than that in survival flap group,and the level of FIB was higher than that in survival flap group(P<0.05).The two-column correlation analysis showed that FIB level was positively correlated with flap inactivation after flap repair in patients with soft tissue defect after hand injury(r>0,P<0.05),and ALB level was negatively correlated with flap inactivation after flap repair in patients with soft tissue defect after hand injury(r<0,P<0.05).Conclusion:The expression of ALB and FIB is related to the deactivation of skin flap in patients with soft tissue defect after hand injury.Low expression of ALB and high expression of FIB may increase the risk of skin flap deactivation after skin flap repair.
hand traumaSoft tissue defectChest and abdomen pedicled flap repairAlbuminFibrinogenFlap inactivation
NETL
NSTL
万方数据
维普
