Changes of bone metabolism indexes and curative effect of Xianling Gubao capsule in patients with type 2 diabetes mellitus
Objective:To explore the changes of bone metabolism indexes and curative effect of Xianling Gubao capsule in patients with type 2 diabetes mellitus(T2DM).Methods:A total of 200 patients with T2DM and osteoporosis(OP)admitted to the department were enrolled as the research objects between January 2022 and June 2023.According to simple random grouping method,they were divided into study group and control group,100 cases in each group.After 12 weeks of continuous treatment,bone metabolism indexes,bone mineral density and adverse reactions in the two groups were compared.Results:After treatment,total response rates of treatment in study group was significantly higher than that in control(P<0.05).After treatment,25-hydroxy vitamin D[25-(OH)D]and bone glaprotein(BGP)were significantly increased in both groups(P<0.05),which were significantly higher in study group than control group(P<0.05),calcium(Ca)and phosphorous(P)were also significantly increased(P<0.05),which were significantly higher in study group than control group(P<0.05).After treatment,there was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion:Xianling Gubao capsule can improve bone metabolism indexes in patients with T2DM and OP,with significant curative effect and high safety.
Type 2 diabetes mellitusBone metabolism indexXianling Gubao capsule
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