Effect of Xiaozhong Shengji Decoction Assisted LIFT on Postoperative Pain and Rehabilitation Progress of High Simple Anal Fistula
Objective:To investigate the effect of XiaozhongShengji decoction assisted Ligation of intersphincteric fistula(LIFT)on Visual analogue scale(VAS)score and rehabilitation process of postoperative high simple anal fistula.Methods:Ninety-four patients with anal fistula diagnosed in our hospital from August 2020 to August 2022 were selected as study subjects and divided into study group and control group according to randomized control method,with 47 cases each.The control group was treated with LIFT,and the study group was treated with XiaozhongShengji decoction based on the control group.The clinical efficacy,recovery after treatment,length of stay,visual analogue score(VAS),Fecal incontinence severity index(FISI),Wexner anal incontinence score(Wexner),anorectal dynamics,and related serum index levels were compared between the two groups.Results:The total effective rate of the study group was higher than that of the control group(P<0.05).After treatment,VAS,FISI and Wexner scores in the study group were lower than those in the control group(P<0.05).Rectal resting pressure(RRP),Analmaximal contraction pressure(AMCP),Anal tube resting pressure(RRP),The levels of ARP and Anal longest contraction(ALCT)were higher than those of control group,and were close to the level before treatment(P<0.05).The serum transforming growth factor-β1(TGF-β1)and fibronectin(FN)in the study group were higher than the control group,and the serum amyloid A(SAA)and chemokine ligand 5(CCL5)were lower than the control group(P<0.05).CCL5 were lower than those in the control group(P>0.05),the recovery and hospital stay in the study group were shorter than the control group(P<0.05).Conclusion:XiaozhongShengji Decoction assisted LIFT has significant postoperative effect on patients with high simple anal fistula,which can effectively promote wound healing,reduce inflammatory response,reduce anorectal pain,and shorten clinical rehabilitation process.
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