Value of Lymph Node Morphology Delineated on Contrast-Enhanced Scan in Predicting Regional Lymph Node Metastasis of Hepatocellular Carcinoma
Objective:To evaluate the value of lymph node morphology delineated on contrast-enhanced computed tomography(CT)scan in predicting regional lymph node metastasis of hepatocellular carcinoma.Methods:Eighty-six patients with hepatocellular carcinoma in our hospital from March 2020 to June 2022 were selected.None underwent neoadjuvant chemoradiotherapy before surgery,and all were subjected to the contrast-enhanced scans.Using pathological findings as the gold standard,patients were divided into metastasis group and non-metastasis group.The diagnostic value of the morphological criteria of contrast-enhanced CT scans versus traditional criteria for lymph node metastasis was evaluated,and the consistency between two criteria and gold standard was assessed using receiver operating characteristic curve(ROC).Results:Among the 86 patients with hepatocellular carcinoma,there were 38 cases with lymph node metastasis and 48 cases without metastasis.The sensitivity,specificity,accuracy and positive predictive value and negative predictive value of morphological criteria on contrast-enhanced CT scans were higher than those of traditional criteria.Morphological criteria revealed good consistency with the gold standard for diagnosing lymph node metastasis(Kappa=0.764).Conclusion:The lymph node morphology delineated on contrast-enhanced scan yields good sensitivity,specificity,accuracy,positive predictive value,and negative predictive value for regional lymph node metastasis of hepatocellular carcinoma,and are all higher than those of traditional standards,which shows good consistency with the gold standard.
Contrast-enhanced CTLymph node morphologyHepatocellular carcinomaLymph node metastasisPredictive value