Effects of different total hysterectomy on stress response and microinflammatory factors in patients with myoadenosis
Objective:To investigate the effects of different total hysterectomy on stress response and microinflammatory factors in patients with myoadenosis.Methods:94 patients with myoadenosis treated in our hospital from January 2020 to January 2023 were selected as subjects.All patients were divided into TAH group(n=44)and LTH group(n=50)according to different surgical methods.The TAH group was treated with Transabdominal hysterectomy(TAH).The LTH group was treated by Laparoscopic total hysterectomy(LTH).The perioperative indexes,stress response,microinflammatory factors and postoperative pain were analyzed and compared between the two groups.Results:The specific amount of blood loss,the specific time of operation,the specific time of postoperative exhaust and the specific days of postoperative hospitalization in LTH group were lower than those in TAH group(P<0.05).The levels of Corticosteroids(COR),AngiotensinⅡ,AngⅡ and Epinephrine E in the LTH group were lower than those in the TAH group(P<0.05).The levels of Procalcitonin(PCT),Interleukin-6(IL-6)and C-reactive protein(CRP)in the LTH group were lower than those in the TAH group(P<0.05).Pain scores 12 hours,1 day and 3 days in LTH group were lower than those in TAH group(P<0.05).Conclusion:Compared with TAH operation,LTH operation has the advantages of less trauma,less bleeding,less postoperative stress and inflammation reaction,and faster recovery.
MyoadenosisLaparoscopic total hysterectomyOpen total hysterectomyStress responseMicroinflammatory factor
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