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产后阴道微生态的定性系统评价

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目的:分析产后阴道微生态体系4项核心主题的变化,包含产后菌群结构特征、菌型(Community state types,CST)分布、生物多样性、与孕期及非孕期的差异性菌属.方法:使用Vaginal/Vaginas/Reproductive tract,Microbiota/Flora,Microbiome/Microbiotas/Microbial/Microbiome/Microbiomes,Postpartum Period/Postpartum/Puerperium在9个中英文数据库进行检索,共得出 1783 篇文献,最终筛选 10 篇文献纳入分析,并采用关键评价方案(Critical Appraisal Skills Program,CASP)工具进行文献质量评价.结果:10篇文章对4项核心主题纳入分析,产后生殖道菌群呈现特征性菌群结构,以厌氧菌为优势菌,多由 CST Ⅲ、CST Ⅳ-A构成.产后的阴道微生态菌种多样性,与非孕期健康女性无明显差异,与妊娠期相比其α多样性和β多样性均最高.产后的乳酸杆菌丰度降低,而种类增多.结论:提示可对产后妇女尝试采取有效的治疗措施来,尽快改善产后阴道微环境向健康非孕期妇女转化.
Qualitative systematic evaluation of postpartum vaginal microecology
Objective:To analyze the changes in four core themes of postpartum vaginal microecosystem,including the structural characteristics of postpartum flora,the distribution of community state types(CST),biodiversity,and the differences between pregnant and non-pregnant bacterial genera.How:Using Vaginal/Vaginas/Reproductive tract Microbiota/Flora,Microbiome Microbiotas/Microbial/Microbiome/Microbiomes,Postpartum Period Postpartum/Puerperium in 9 Chinese English database retrieval,a total of 1783 articles,ultimately selected 10 articles were included in the analysis,Critical Appraisal Skills Program(CASP)was used to evaluate the quality of documents.Results:10 articles included 4 core topics in the analysis,the postpartum reproductive tract flora showed a characteristic flora structure,with anaerobic bacteria as the dominant bacteria,mostly composed of CST Ⅲ and CST Ⅳ-A.The diversity of postpartum vaginal microecological bacteria was not significantly different from that of non-pregnant healthy women,and the α diversity and β diversity were the highest compared with pregnancy.The abundance of lactobacillus decreased after delivery,but the variety increased.Conclusion:It is suggested that effective treatment measures can be taken to improve the transformation of postpartum vaginal microenvironment to healthy non-pregnant women as soon as possible.

postpartumVaginal microecologyQualitative system evaluation

闫梅、王晓银、罗同勇、帅志容、李宁、王玉敏

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四川省妇幼保健院﹒四川省妇女儿童医院,四川 成都 610000

成都中医药大学附属医院,四川 成都 610000

四川省妇幼保健院米易分院﹒米易县妇幼保健院,四川 攀枝花 610000

产后 阴道微生态 定性系统评价

2024

四川生理科学杂志
四川省生理科学会

四川生理科学杂志

影响因子:0.575
ISSN:1671-3885
年,卷(期):2024.46(3)
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