Effects of HFNC airway management on oxygenation status,hemodynamics and lung compliance in patients with acute hypoxic respiratory failure examined by bedside painless fiberoptic bronchoscopy
Objective:To explore the effects of airway management in high-flow nasal oxygen therapy(HFNC)on oxygenation state,hemodynamics and lung compliance of patients with Acute hypoxic respiratory failure(AHRF)examined by bedside painless fiberoptic bronchoscopy.Methods:120 patients with AHRF who planned to undergo bedside painless fiberoptic bronchoscopy from December 2021 to December 2022 were randomly divided into NPPV group and HFNC group,with 60 patients in each group.Non-invasive positive pressure ventilation(NPPV)airway management was performed in NPPV group,and HFNC airway management was performed in HFNC group.After the intervention,the oxygenation status,hemodynamic level and lung compliance were compared between the two groups.Results:At T2,the oxygen partial pressure and oxygenation indexes in HFNC group were higher than those in NPPV group,and the carbon dioxide partial pressure was lower than that in NPPV group(P<0.05).At T1 and T2,the changes of hemodynamic levels in HFNC group were smaller than those in NPPV group(P<0.05).The total compliance,lung compliance and thoracic compliance in HFNC group were higher than those in NPPV group 3 days after operation(P<0.05).Conclusion:HFNC airway management can effectively improve oxygenation status,hemodynamics,and lung compliance in patients with AHRF bedside painless bronchoscopy.