目的:探究丁苯酞辅助治疗对急性缺血性脑卒中血液流变学及神经保护作用.方法:选取本院 2020年 12 月至 2023 年 7 月收治的急性缺血性脑卒中患者 87 例,根据治疗方案不同分为对照组 42 例(常规治疗)和观察组45 例(丁苯酞辅助治疗).观察并比较两组临床疗效、血液流变学指标、神经功能状态(美国国立卫生院量表(National Institute of Health stroke scale,NIHSS)、改良型Rankin量表(Modified Rankin Scale,mRS))和不良反应.结果:观察组总有效率明显高于对照组(P＜0.05);治疗后两组各血液流变学指标值、NIHSS评分、mRS评分均明显下降,且观察组各指标值均低于对照组(P＜0.05);两组均未见严重不良反应.结论:丁苯酞辅助治疗可有效改善急性缺血性脑卒中患者血液流变学,并促进神经功能恢复,其临床疗效显著,安全性较好.
Analysis of the hemorheological and neuroprotective effects of butylphthalide assisted treatment in acute ischemic stroke
Objective:To investigate the hemorheological and neuroprotective effects of butylphthalide assisted treatment in acute ischemic stroke.Methods:Eighty-seven patients with acute ischemic stroke admitted to our hospital from December 2020 to July 2023 were selected and divided into the control group(conventional treatment,42 cases)and the observation group(butylphthalide-assisted treatment,45 cases),according to different treatments.The clinical efficacy,blood rheological indexes,neurological function status(National Institute of Health stroke scale(NIHSS),Modified Rankin Scale(mRS))and adverse reactions were observed and compared between the two groups.Results:The total effective rate of the observation group was significantly higher than that of the control group(P<0.05);the levels of all hemorheological indexes,NIHSS scores and mRS scores of the two groups decreased significantly after treatment,and all the indexes in the observation group were lower than those in the control group(P<0.05);and there were no serious adverse reaction in the two groups.Conclusion:Butylphthalide-assisted treatment can effectively improve the hemorheology of patients with acute ischemic stroke and promote the recovery of neurological function,with good clinical efficacy and safety.
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万方数据
维普
