Study on pathologic consistency of endoscopic acetic acid staining combined with narrow band light imaging in early diagnosis of gastric cancer
Objective:To study the pathological consistency of endoscopic acetic acid staining combined with NBI in early diagnosis of gastric cancer.Methods:A total of 127 patients with suspected early gastric cancer admitted to our hospital from January 2021 to December 2022 were selected as the study objects.All subjects underwent conventional gastroscopy,NBI alone,and NBI combined with endoscopic acetic acid staining examination.Compare the sharpness of the three inspection images;Taking pathological examination as the"gold standard",the detection rate,diagnostic value and consistency with pathological examination were analyzed.Results:118 patients with early gastric cancer were confirmed by pathological examination.The resolution ratio of lesion contour,mucosal glandular duct opening and superficial capillary structure in 3 points:NBI combined with endoscopic acetic acid staining examination>simple NBI>conventional gastroscopy,with statistical significance between groups(P<0.05).99 cases were detected by routine gastroscopy,103 cases by NBI alone,and 115 cases by NBI and endoscopic acetic acid staining.The sensitivity,specificity,diagnostic coincidence rate,PPV and NPV of NBI combined with endoscopic acetic acid staining examination were significantly higher than those of NBI alone and routine gastroscopy(P<0.05).After Kappa test,the consistency of NBI combined with endoscopic acetic acid staining examination with gold standard was higher than that of conventional gastroscopy and NBI alone(P<0.05).Conclusion:Endoscopic acetic acid staining combined with NBI can clearly show the morphology of microvessels and microglandular tubes in early gastric cancer,which is superior to NBI and routine examination,and has excellent consistency with the pathological examination of early gastric cancer.The combination of the two has high diagnostic value in the early diagnosis of gastric cancer.