目的:探究衰弱对社区获得性肺炎患者的临床疗效及生活质量的影响.方法:选取 2022 年1 月至 2023 年8月期间我院收治的 60 例获得性肺炎患者作为研究对象.按照患者的衰弱表型评估方法(Fried衰弱评估)评分是否小于 3 分将患者分为非衰弱组(n=23)和衰弱组(n=37).根据《中国成人社区获得性肺炎诊断和治疗指南》的建议,对患者采取相应的治疗措施.比较两组患者临床疗效、临床症状消退时间、肺功能[第 1 秒用力呼气量(First second forced expiratory volume,FEV1)、用力肺活量(Forced vital capacity,FVC)及FEV1与FVC的比值(Ratio of FEV1 to FVC,FEV1/FVC)]、生活质量[生活质量量表(SF-36)]的差异.结果:治疗后 4 w,衰弱组的总有效率明显低于非衰弱组(P＜0.05);衰弱组患者的临床症状消失时间明显长于非衰弱组(P＜0.05);两组患者 FEV1、FVC、FEV1/FVC肺功能明显高于治疗前,但衰弱组明显低于非衰弱组(P＜0.05);衰弱组患者的生活质量指标评分明显低于非衰弱组(P＜0.05).结论:针对社区获得性肺炎患者,衰弱对临床疗效有负面影响,会延长患者的临床症状消退时间,影响患者肺功能恢复,降低患者的生活质量.
Effects of asthenia on clinical curative effect and quality of life in patients with community-acquired pneumonia
Objective:To explore the effects of asthenia on clinical curative effect and quality of life in patients with community-acquired pneumonia(CAP).Methods:A total of 60 patients with CAP in the hospital were enrolled as the research objects between January 2022 and August 2023.According to presence or absence of asthenia(evaluation by scores of Fried asthenia assessment),they were divided into non-asthenia group(n=23,<3 points)and asthenia group(n=37).According to recommendations in Guidelines for the Diagnosis and Treatment of Community-Acquired Pneumonia in Chinese Adults,patients were given corresponding treatment.The clinical curative effect,disappearance time of clinical symptoms,lung function[first second forced expiratory volume(FEV1),forced vital capacity(FVC),ratio of FEV1 to FVC(FEV1/FVC)]and quality of life[the 36-item shot-form health status survey(SF-36)]were compared between the two groups.Results:At 4 weeks after treatment,total response rate of asthenia group was significantly lower than that of non-asthenia group(P<0.05).The disappearance time of clinical symptoms in asthenia group was significantly longer than that in non-asthenia group(P<0.05).After treatment,FEV1,FVC and FEV1/FVC were significantly increased in both groups,which were significantly lower in asthenia group than non-asthenia group(P<0.05).The quality of life index scores in asthenia group were significantly lower than those in non-asthenia group(P<0.05).Conclusion:Asthenia has negative effects on clinical curative effect in CAP patients,which will prolong disappearance time of clinical symptoms,affects the recovery of lung function and reduce quality of life.
AstheniaCommunity-acquired pneumoniaClinical curative effectQuality of life
NETL
NSTL
万方数据
维普
