Effect of intravenous pumping of dexmedetomidine on hemodynamics in elderly patients with hip fracture surgery after successful combined spinal-epidural anesthesia
Objective:To explore the effect of intravenous pumping of dexmedetomidine on hemodynamics after successful combined spinal-epidural anesthesia for elderly hip fractures.Methods:70 elderly patients with hip fractures admitted to our hospital from June 2018 to August 2023 were selected and divided into control group and observation group randomly,with 35 cases in each group.Control group was given conventional combined spinal-epidural anesthesia,and observation group was given intravenous pumping of dexmedetomidine after successful anesthesia.The two groups were observed in terms of hemodynamic changes[including systolic blood pressure(SBP),diastolic blood pressure(DBP),heart rate(HR)and oxyhemoglobin saturation(SpO2)immediately after anesthesia(T0),after incision making(T1),after replacement/nail implantation(T2)and at skin suture after the end of surgery(T3)],sedation effect(Richmond Agitation and Sedation Scale(RASS)at T0,T1,T2 and T3),and adverse reactions of anesthetic drugs.Results:The SBP,DBP and HR in observation group were lower than those in control group at T1,T2 and T3(P<0.05).The SpO2 and moderate rate of sedation were similar between the two groups of patients.The incidence rates of adverse reactions of anesthetic drugs were similar between the two groups.Conclusion:Intravenous pumping of dexmedetomidine has good sedation effect and analgesia effect and high safety after successful combined spinal-epidural anesthesia in elderly patients undergoing hip fracture surgery.
NETL
NSTL
万方数据
维普
