Effects of intraoperative maintenance anesthesia with remimazolam and propofol on hemodynamics and recovery quality in elderly patients undergoing surgery under general anesthesia
Objective:To investigate the effects of maintenance anesthesia with remimazolam and propofol on hemodynamics and recovery quality in elderly patients undergoing surgery under general anesthesia.Methods:A total of 70 patients who underwent surgery under general anesthesia from March 2020 to May 2023 in our hospital were selected as the study subjects.They were divided into a control group and an observation group using the random number table method,with 35 cases in each group.The control group received intraoperative maintenance anesthesia with propofol while the observation group received intraoperative maintenance anesthesia with remimazolam.Hemodynamics,awakening quality,and the incidence rates of adverse reactions were compared between the two groups.Results:There was no statistically significant difference in mean arterial pressure(MAP)or heart rate(HR)of the observation group at different time points(P>0.05).Only oxygen saturation(SPO2)at 1 minutes after intubation(T2)was lower than that before anesthesia induction(T0)(P<0.05).MAP and HR of the control group showed statistically significant differences at different time points(P<0.05).Comparison between groups found that MAP at T1 and T2 and HR at T1 were significantly higher in the observation group than in the control group,while HR at T2 was significantly lower than the control group(P<0.05).Postoperative extubation time,eye opening time at request and spontaneous breathing time of the observation group were shorter than those of the control group(P<0.05).The incidence of postoperative adverse reactions in the observation group was lower than that in the control group(P<0.05).Conclusion:Compared with propofol,intraoperative use of remimazolam can stabilize hemodynamic indicators in elderly patients and improve postoperative recovery quality,with fewer adverse reactions and higher safety.
Surgery under general anesthesiaIntraoperativeRemimazolamPropofolMaintenance anesthesiaElderlyHemodynamicsRecovery quality
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