Effect of high flow nasal cannulae oxygen therapy combined with injection of cefoperazone sodium and sulbactam sodium in the treatment of neonatal infectious pneumonia
Objective:To analyze the efficacy of high flow nasal cannula oxygen therapy(HFNC)combined with injection of cefoperazone sodium and sulbactam sodium in the treatment of neonatal infectious pneumonia(NIP).Method:64 children with NIP admitted to our hospital from January 2021 to September 2023 were selected as the study subjects,and randomly divided into a control group and an observation group,with 32 cases in each group.The control group was given cefoperazone sodium and sulbactam sodium for injection.The observation group received HFNC treatment on the basis of the control group.The curative effect,blood gas indexes and recovery of the two groups were analyzed and compared.Result:After treatment,the total effective rate of the observation group was significantly higher than that of the control group(P<0.05).After treatment,both groups showed an increase in partial pressure of oxygen(PaO2)and pulse oxygen saturation(SpO2),while a decrease in partial pressure of carbon dioxide(PaCO2).The observation group had higher levels of PaO2 and SpO2 than the control group,while PaCO2 was lower than the control group(P<0.05).The disappearance time of clinical symptoms and hospitalization time in the observation group were significantly shorter than those in the control group(P<0.05).Conclusion:The combination of HFNC and cefoperazone sodium and sulbactam sodium for injection in the treatment of NIP can improve clinical efficacy,improve the blood gas status of patients,and promote their recovery.
Neonatal infectious pneumoniaHigh flow nasal cannula oxygen therapyCefoperazone sodium and sulbactam sodiumBlood gas analysis
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