首页|无痛宫颈环形电切术治疗早期宫颈癌前病变的临床效果及安全性分析

无痛宫颈环形电切术治疗早期宫颈癌前病变的临床效果及安全性分析

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目的:探究无痛宫颈环形电切术治疗早期宫颈癌前病变的临床效果及安全性.方法:选择 2020年 1 月至 2022年 12 月收治的 80 例宫颈前癌变患者,参照随机数表法将其分为对照组及观察组,每组 40 例.对照组行常规手术,观察组行无痛宫颈环形电切术.术后开展复查随访 1 y,比较术后 1 m两组临床效果、手术时间、术中出血量及术后阴道脱痂期出血时间等临床指标;采用癌症患者生命质量评估量表对比术前、术后 1 m两组生活质量差异;比较 1 m内两组并发症发生率以及术后 1 y内复发率.结果:术后 1 m复查结果显示,观察组总临床有效率及满意度均高于对照组(P<0.05);观察组手术时间、术中出血量及术后阴道脱痂期出血时间均低于对照组(P 均<0.05);术后 1 m后两组生活质量评分均高于术前,且观察组高于对照组(P均<0.05);术后 1 m,观察组总并发症率均低于对照组(P<0.05);术后 1 y内,观察组总复发率低于对照组(P<0.05).结论:无痛宫颈环形电切术治疗早期宫颈癌前病变效果确切,对患者的创伤性更小,术后恢复较快,并发症风险轻,有助于提升患者生活质量.
Clinical effect and safety of painless loop electrical excision procedure on early cervical precancerous lesions
Objective:To explore the clinical effect and safety of painless loop electrical excision procedure in the treatment of early cervical precancerous lesions.Methods:80 patients with cervical precancerous lesions admitted from January 2021 to December 2022 were selected and divided into control group and observation group by using a random number table method,with 40 cases in each group.The control group underwent routine surgery,while the observation group received painless loop electrical excision procedure.The clinical indicators such as clinical effect at 1 month after surgery,surgical time,intraoperative bleeding volume,and postoperative vaginal scab shedding bleeding time,quality of life(Core Quality of Life Questionnaire(QLQ-C30))before surgery and at 1 month after surgery,incidence rates of complications within 1 month and recurrence rate within 1 year after surgery were compared.Results:Reexamination results at 1 month after surgery showed that the total clinical effective rate and satisfaction in observation group were higher than those in control group(P<0.05).The observation group had shorter surgical time,less intraoperative bleeding volume and shorter postoperative vaginal scab shedding bleeding time compared to the control group(all P<0.05).At 1 month after surgery,the QLQ-C30 scores of both groups were higher than before surgery,and the scores in observation group were higher(all P<0.05).The total complication rate in the observation group at 1 month after surgery was lower than that in the control group(P<0.05).Within 1 year after surgery,the total recurrence rate were lower in the observation group(P<0.05).Conclusion:Painless loop electrical excision procedure has an exact effect in treating early cervical precancerous lesions,and it has small trauma to patients,fast postoperative recovery and low risk of complications,and it can help improve the quality of life of patients.

Painless loop electrical excision procedureEarly cervical precancerous lesionsClinical effectSafetyQuality of life

张琼

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于都县妇幼保健院,江西 赣州 342300

无痛宫颈环形电切术 早期宫颈癌前病变 临床效果 安全性 生活质量

2024

四川生理科学杂志
四川省生理科学会

四川生理科学杂志

影响因子:0.575
ISSN:1671-3885
年,卷(期):2024.46(6)