Effects of Suzi Jiangqi Decoction combined with Tiotropium bromide and odatterol on pulmonary function and serum inflammatory mediators in patients with chronic obstructive pulmonary disease
Objective:To investigate the effect of Suzi Jiangqi Decoction combined with tiotropium bromide and odatterol in the treatment of Chronic obstructive pulmonary disease(COPD).Methods:94 patients with COPD admitted to our hospital from January 2021 to February 2023 were selected as the study objects.Patients were randomly divided into observation group and control group,with 47 cases in each group.The control group received tiotropium bromide and odatterol treatment.The observation group was treated with Suzi Jiangqi Decoction based on the control group,and both groups were treated continuously for 1 month.The efficacy,lung function(first expiratory volume in one second(FEV1),forced vital capacity(FVC)),serum inflammatory mediators'interleukin-6(IL-6),tumor necrosis factor-α(TNF-α)and adverse reactions were analyzed and compared between the two groups.Results:After treatment,the total effective rate of observation group was significantly higher than that of control group(P<0.05).After treatment,the levels of FEV1 and FVC in both groups were significantly higher than before treatment,and the levels of FEV1 and FVC in observation group were significantly higher than those in control group(P<0.05).After treatment,the serum levels of IL-6 and TNF-α in 2 groups were significantly lower than before treatment,and the serum levels of IL-6 and TNF-α in observation group were significantly lower than those in control group(P<0.05).There were no obvious adverse reactions during treatment in both groups(P>0.05).Conclusion:Tiotropium bromide and odatterol combined with Suzi Jiangqi Decoction in the treatment of COPD can improve the curative effect,improve lung function,inhibit inflammation,and have high safety.
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