首页|利湿消肿丸辅助治疗膝骨性关节炎伴关节腔积液的临床分析

利湿消肿丸辅助治疗膝骨性关节炎伴关节腔积液的临床分析

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目的:探讨利湿消肿丸辅助治疗膝骨性关节炎伴关节腔积液的效果.方法:选取本院 2021 年1 月至 2023 年1 月确诊的 66 例膝骨性关节炎伴关节腔积液患者作为研究对象.随机数字表法将患者分为对照组和观察组,每组各 33 例.对照组进行常规治疗,观察组在对照组基础上口服利湿消肿丸辅助治疗,两组均连续治疗 3 w.治疗 3 w后依据中药新药临床研究指导原则中疗效标准评估两组的疗效;治疗前、治疗 3 w后采用超声检测关节积液量、采用视觉模拟评分法(Visual analogue scale,VAS)评估疼痛程度.结果:观察组治疗总有效率高于对照组(P<0.05);与治疗前比较,两组治疗后关节积液量均减少,且观察组减少更为显著(P<0.05);两组治疗后VAS评分均降低,且观察组降低更为显著(P<0.05).结论:给予膝骨性关节炎伴关节腔积液患者利湿消肿丸辅助治疗,临床疗效显著,可减少患者关节积液量,缓解患者疼痛程度.
Clinical analysis of the adjuvant treatment of knee osteoarthritis with joint effusion with Lishi Xiaotuo Pill
Objective:To investigate the effect of Lishi Xiaotuo pill in the treatment of knee osteoarthritis with joint effusion.Methods:66 patients with knee osteoarthritis with joint effusion diagnosed in our hospital from January 2021 to January 2023 were selected as the study objects.Patients were divided into control group and observation group by random number table method,with 33 cases in each group.The control group received conventional treatment,and the observation group received oral treatment with Lishi Xiaotuo pill on the basis of the control group.Both groups received continuous treatment for 3 weeks.After 3 weeks of treatment,the efficacy of the two groups was evaluated according to the therapeutic criteria in the guidelines for clinical research of new Chinese medicine.Before and 3 weeks after treatment,the amount of joint effusion was detected by ultrasound,and the degree of pain was assessed by visual analogue scale(VAS).Results:The total effective rate of observation group was higher than that of control group(P<0.05).Compared with before treatment,the amount of joint effusion decreased in both groups after treatment,and the decrease was more significant in the observation group(P<0.05).VAS scores of both groups were decreased after treatment,and the decrease was more significant in the observation group(P<0.05).Conclusion:The adjuvant treatment of Lishi Xiaotuo pill for patients with knee osteoarthritis with joint effusion has significant clinical effect,which can reduce the amount of joint effusion and relieve the pain degree of patients.

Lishi Xiaotuo pillKnee osteoarthritisFluid accumulation in joint space

魏春霞

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郑州中医骨伤病医院制剂室,河南 郑州 450047

利湿消肿丸 膝骨性关节炎 关节腔积液

2024

四川生理科学杂志
四川省生理科学会

四川生理科学杂志

影响因子:0.575
ISSN:1671-3885
年,卷(期):2024.46(6)