肺淋巴上皮癌的研究进展
Research progress of lung lymphoepithelial carcinoma
陈思林 1李婷婷 1冯旭琴 1王丹 1胡欣1
作者信息
- 1. 南充市中心医院肿瘤中心(首都医科大学附属北京安贞医院南充医院)/川北医学院第二临床医学院,四川 南充 637000
- 折叠
摘要
肺淋巴上皮癌(Pulmonary Lymphoepithelial-like carcinoma,pLEC)是一种罕见的非小细胞肺癌(Non-small cell lung cancer,NSCLC),2021 年(World health organization,WHO)将其归类于肺鳞状细胞癌的一个亚型.pLEC的流行病学、临床病理特征、诊断治疗及预后均不同于常见的非小细胞肺癌.pLEC的发生发展和EB病毒(Epstein-Barr virus,EBV)感染密切相关,其预后明显好于常见的NSCLC.近年来有关pLEC的研究有了明显的进展,本文将就pLEC的研究进展进行综述,以促进pLEC的规范化诊断治疗.
Abstract
Pulmonary Lymphoepithelial-like carcinoma(pLEC)is a rare type of non-small cell lung cancer(NSCLC).In 2021,the World health organization(WHO)classified it as a subtype of lung squamous cell carcinoma.The epidemiology,clinicopathological features,diagnosis,treatment and prognosis of pLEC are different from those of common non-small cell lung cancer.The occurrence and development of pLEC is closely related to Epstein-Barr virus(EBV)infection,and its prognosis is significantly better than that of common NSCLC.In recent years,the research on pLEC has made remarkable progress.This article will review the research progress on pLEC in order to promote the standardized diagnosis and treatment of pLEC.
关键词
肺淋巴上皮癌/EB病毒/PD-1/PD-L1/免疫治疗Key words
lung lymphoepithelial carcinoma/EB virus/PD-1/PD-L1/immunotherapy引用本文复制引用
出版年
2024
NETL
NSTL
万方数据