Effects of salbutamol combined with cetirizine on the levels of immunoglobulin and related cytokines in children with allergic cough
Objective:To investigate the effect of salbutamol and cetirizine combined therapy in patients with allergic cough.Methods:A total of 120 children with allergic cough in our hospital from December 2021 to February 2024 were selected,and they were divided into groups using a random number table method.The reference group consisted of 60 cases treated with cetirizine;60 cases in the experimental group were treated with cetirizine and salbutamol,and both groups were treated continuously for 2 weeks.Observe the levels of immunoglobulins,inflammatory factors,cough symptoms,and incidence of adverse reactions in two groups.The occurrence of two groups of immunoglobulin,inflammatory factors,cough symptoms and adverse reactions were Observed.Results:The levels of serum immunoglobulin IgG,IgA,and IgM in both groups after treatment were higher than before treatment,and the experimental group was higher than the reference group(P<0.05);Serum IL-6 and TNF after two groups of treatment-α The level was lower than before treatment,but there was no significant difference between the two groups(P>0.05);Compared to before treatment,the cough symptom scores of both groups after treatment were lower,and the experimental group was lower than the reference group(P<0.05);There is not much difference in the total incidence of adverse reactions between the two groups of children.Conclusion:The combination regimen of salbutamol and cetirizine can improve the immune function,inhibit the inflammation and improve the cough control effect in children with allergic cough without increasing the adverse reactions.
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