Effects of nebulized budesonide inhalation assisted azithromycin treatment on disease control,CRP and WBC in children with Mycoplasma pneumoniae pneumonia
Objective:To investigate the effects of nebulized budesonide inhalation assisted azithromycin treatment on disease control,C-reactive protein(CRP)and white blood cell count(WBC)in children with Mycoplasma pneumoniae pneumonia(MPP).Methods:Sixty children with MPP admitted to the hospital from September 2023 to January 2024 were selected as the study subjects,and assigned to the observation group and the control group using the random number table method,with 30 cases in each group.The control group was treated with oral azithromycin and the observation group was treated with nebulized budesonide inhalation on this basis.Clinical symptoms,disease control,CRP and WBC were compared between the two groups,and the incidence rates of adverse reactions were calculated.Results:After treatment,the time for cough and fever disappearing in the observation group was shorter than that in the control group(P<0.05).After treatment,forced expiratory volume in one second(FEV1),forced vital capacity(FVC),peak respiratory flow(PEF)and peak expiratory flow at 25%of vital capacity(PEF25)in both groups increased significantly(P<0.05).Compared to the control group,the observation group had higher FEV1,FVC,PEF,and PEF25(P<0.05).There was no statistically significant difference in CRP level or WBC between the two groups before treatment(P>0.05).After treatment,there were significant decreases in CRP level and WBC in both groups.Meanwhile,the two indicators in the observation group were lower than those in the control group(P<0.05).After treatment,adverse reactions in the two groups were comparable(P>0.05).Conclusion:Budesonide assisted azithromycin treatment is effective for children with MPP,which can effectively alleviate clinical symptoms,without significant side effects.
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