Clinical,pathogenic characteristics,and biochemical indicators analysis of different types of neonatal sepsis
Objective:To analyze and explore the clinical,pathogenic characteristics,and biochemical differences of different types of neonatal sepsis.Methods:Sixty cases of neonatal sepsis patients with positive blood culture admitted to our hospital from January 2021 to December 2023 were selected.Thirty cases of early onset neonatal sepsis(EONS)were included in Group A,and thirty cases of late onset neonatal sepsis(LONS)were included in Group B.The clinical manifestations,pathogen distribution,drug resistance,and biochemical indicators were collected and compared between two groups.Results:The proportion of h gestational age<37 weeks,birth weight<2.5 kg,and fever incidence in Group A were lower than those in Group B(P<0.05);The incidence of neonatal asphyxia,amniotic fluid pollution,jaundice and milk retention in group A were higher than those in group B(P<0.05).The pathogenic bacteria in Group A are mainly Gram positive bacteria,with the highest sensitivity to vancomycin and teicoplanin;The pathogenic bacteria in Group B are mainly Gram negative bacteria,with the highest sensitivity to imipenem and meropenem.The PLT of Group A was lower than that of Group B(P<0.05);The MPV of Group A was higher than that of Group B(P<0.05).Conclusion:There are certain differences in clinical manifestations,pathogen distribution,and biochemical indicators among children with different types of neonatal sepsis.Clinical attention should be paid to differential diagnosis,and antibiotic treatment should be selected based on drug sensitivity results,to avoid antibiotic abuse.
NETL
NSTL
万方数据
