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卡络磺钠联合血凝酶在急性上消化道出血治疗中的应用

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目的:分析急性上消化道出血经卡络磺钠联合血凝酶治疗的效果.方法:选取 2020年 1 月至 2023 年 10 月期间本院收治的 76 例急性上消化道出血患者作为研究对象,采用随机数字表法将患者分为对照组和观察组,各38 例.对照组采用血凝酶常规治疗,观察组在对照组基础上增加采用卡络磺钠治疗,两组均连续治疗 3 d.分析比较两组止血时间、住院时间、凝血功能、不良反应发生情况.结果:治疗后,观察组止血时间、住院时间均明显短于对照组(P<0.05);观察组纤维蛋白原均明显高于对照组、活化部分凝血活酶时间和凝血酶原时间均明显短于对照组(P<0.05).两组不良反应发生率无明显差异(P>0.05).结论:卡络磺钠联合血凝酶能够在短时间内帮助急性上消化道出血患者止血,改善凝血功能,促进患者康复,减少住院时间,且具有较高的治疗安全性.
Application of carbazol sodium sulfonate combined with hemagglutinin in the treatment of acute upper gastrointestinal bleeding
Objective:To analyze the effect of carbazol sodium sulfonate combined with hemagglutinin in the treatment of acute upper gastrointestinal hemorrhage.Methods:A total of 76 patients with acute upper gastrointestinal hemorrhage admitted to our hospital from January 2020 to October 2023 were selected as the research objects.The patients were divided into control group and observation group by random number table method,with 38 cases in each group.The control group received routine treatment with hemagglutinin,and the observation group received additional treatment with sodium carbosulfonate on the basis of the control group.Both groups received continuous treatment for 3 days.The hemostatic time,hospital stay,coagulation function and adverse reactions of the two groups were analyzed and compared.Results:After treatment,the hemostatic time and hospitalization time of observation group were significantly shorter than that of control group(P<0.05).The fibrinogen time of observation group was significantly higher than that of control group,and the activated partial thromboplastin time and prothrombin time were significantly shorter than that of control group(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion:Carbazol sodium sulfonate combined with hemagglutinin can help patients with acute upper gastrointestinal hemorrhage to stop bleeding in a short period of time,improve coagulation function,promote patient rehabilitation,reduce hospital stay,and has a high therapeutic safety.

caroxate sodium sulfonateHemagglutininAcute upper gastrointestinal bleedingClinical effectCoagulation function

刘春侠

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夏邑县第二人民医院西药房,河南 夏邑 476400

卡络磺钠 血凝酶 急性上消化道出血 临床疗效 凝血功能

2024

四川生理科学杂志
四川省生理科学会

四川生理科学杂志

影响因子:0.575
ISSN:1671-3885
年,卷(期):2024.46(7)