特布他林联合布地奈德雾化吸入对支气管肺炎患儿症状消退时间及免疫功能的影响
The effect of nebulized inhalation of terbutaline combined with budesonide on symptom resolution time and immune function in children with bronchopneumonia
伍振华 1陈贤娇1
作者信息
- 1. 石城县人民医院儿科,江西 赣州 342700
- 折叠
摘要
目的:探讨特布他林(TBL)联合布地奈德(BUD)雾化吸入对支气管肺炎患儿症状消退时间及免疫功能的影响.方法:选取 2021 年 10 月～2023 年 10 月我院收治的 83 例支气管肺炎患儿作为研究对象,随机分为BUD组(n=42)和TBL组(n=41).BUD组采用BUD雾化吸入治疗,TBL组在BUD组基础上加用TBL.比较两组临床疗效、症状缓解时间、免疫功能及不良反应.结果:TBL组临床总有效率高于BUD组(P＜0.05).TBL组止咳时间、退烧时间、气促缓解时间、湿性肺啰音消失时间较BUD组短(P＜0.05).2 组治疗前IgA、IgM、IgG水平无明显差别(P＞0.05).治疗后,两组各指标均升高,与BUD组相比,TBL组IgA、IgM、IgG更高(P＜0.05).两组不良反应总发生率无明显差别(P＞0.05).结论:TBL联合BUD雾化吸入具有更好疗效,促进支气管肺炎患儿症状消失,改善免疫功能,安全性较好.
Abstract
Objective:To explore the effects of nebulized inhalation of terbutaline(TBL)combined with budesonide(BUD)on symptom resolution time and immune function in children with bronchopneumonia.Methods:83 children with bronchopneumonia admitted to our hospital from October 2021 to October 2023 were selected as the study subjects and randomly divided into BUD group(n=42)and TBL group(n=41).The BUD group received BUD nebulization inhalation treatment,while the TBL group received TBL in addition to the BUD group.Compare the clinical efficacy,symptom relief time,immune function,and adverse reactions between two groups.Results:The total clinical effective rate of the TBL group was higher than that of the BUD group(P<0.05).The cough relief time,fever reduction time,shortness of breath relief time,and disappearance time of wet lung rales in the TBL group were shorter than those in the BUD group(P<0.05).There was no significant difference in the levels of IgA,IgM,and IgG between the two groups before treatment(P>0.05).After treatment,all indicators in both groups increased.Compared with the BUD group,the TBL group had higher levels of IgA,IgM,and IgG(P<0.05).There was no significant difference in the total incidence of adverse reactions between the two groups(P>0.05).Conclusion:The combination of TBL and BUD nebulization inhalation has better therapeutic effects,promotes the disappearance of symptoms in children with bronchopneumonia,improves immune function,and is safe.
关键词
特布他林/布地奈德/雾化/支气管肺炎/症状消退时间/免疫功能Key words
Terbutaline/Budesonide/Atomization/Bronchopneumonia/Symptom resolution time/Immunologic function引用本文复制引用
出版年
2024
NETL
NSTL
万方数据