Effect of laparoscopic cholecystectomy and open surgery on patients with gallstones
Objective:To explore the effects of laparoscopic cholecystectomy and open surgery on patients with gallstones.Methods:The clinical data of 104 patients with cholecystolithiasis admitted to our hospital from May 2019 to October 2023 were retrospectively collected.Patients were divided into the control group(open surgery,n=51)and the observation group(laparoscopic cholecystectomy,n=53)according to the differences in surgical methods.The therapeutic effects of the two groups were analyzed and compared.Substance P,serotonin,and Norepinephrine(NE)were detected by enzyme-linked immunoassay(ELISA)three days after operation.The postoperative recovery of patients was assessed within one week after surgery and the occurrence of postoperative complications was determined before discharge.Results:The effective rate of the observation group was significantly higher than that of the control group(P＜0.05).After 3 days of operation,the levels of substance P,serotonin,and NE in both groups were increased,and all of them in the observation group were significantly lower than those in the control group(P＜0.05).The time of anal exhaust,the time of getting out of bed and the time of hospitalization in the observation group were significantly shorter than those in the control group(P＜0.05).The incidence of postoperative complications in the observation group(5.66%)was markedly lower than that in the control group(19.60%)(P＜0.05).Conclusion:Compared with traditional open surgery,laparoscopic cholecystectomy has a better clinical effect on patients with gallstones,which can alleviate postoperative pain,promote postoperative recovery,and reduce the incidence of complications.
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