首页|醒脑静注射液联合替罗非班在脑梗死中的应用价值及对患者炎症因子的影响

醒脑静注射液联合替罗非班在脑梗死中的应用价值及对患者炎症因子的影响

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目的:选取脑梗死患者对其进行醒脑静注射液联合替罗非班进行治疗,分析其应用价值及对患者炎症因子的影响.方法:我院 2021 年 6 月至 2023 年 6 月收治的脑梗死患者 120 例,按照随机法分为对照组和研究组,每组各60例.对照组行醒脑静注射液治疗,研究组在对照组基础上给予患者替罗非班治疗.比较两组患者炎症因子水平、Barthel指数、血液流变学指标、脑血流动力学各指标、不良反应发生情况以及临床治疗效果.结果:研究组超敏C反应蛋白、肿瘤坏死因子、白介素 6 及白介素 8、血液流变学指标水平、不良反应发生率低于对照组(P<0.05);研究组Barthel指数、脑血流动力学指标水平、临床疗效高于对照组(P<0.05).结论:给予脑梗死患者醒脑静注射液结合替罗非班治疗,能有效改善患者炎症因子水平,且不良反应较少.
Application value of Xingnaojing injection combined with Tirofiban in patients with cerebral infarction and effect on inflammatory factors
Objective:To select patients with cerebral infarction to be treated with Xingnaojing injection combined with Tirofiban,and to analyze its application value and effect on inflammatory factors in patients.Methods:120 patients with cerebral infarction admitted to our hospital from June 2021 to June 2023 were randomly divided into control group and study group,with 60 cases in each group.The control group was treated with Xingnaojing injection,and the study group was treated with tirofiban on the basis of the control group.The levels of inflammatory factors,Barthel index,hemorheology index,cerebral hemodynamics index,occurrence of adverse reactions and clinical therapeutic effect were compared between the two groups.Results:The levels of hypersensitive C-reactive protein,tumor necrosis factor,interleukin-6 and interleukin-8,hemorheology indexes and the incidence of adverse reactions in the study group were lower than those in the control group(P<0.05).The Barthel index,cerebral hemodynamic index and clinical efficacy of the study group were higher than those of the control group(P<0.05).Conclusion:Xingnaojing injection combined with Tirofiban can effectively improve the level of inflammatory factors in patients with cerebral infarction,and the adverse reactions are less.

Xingnaojing injectionTirofibanCerebral infarctionInflammatory factor levels

王孟孟

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南阳医学高等专科学校第二附属医院,河南 南阳 473024

醒脑静注射液 替罗非班 脑梗死 炎症因子水平

2024

四川生理科学杂志
四川省生理科学会

四川生理科学杂志

影响因子:0.575
ISSN:1671-3885
年,卷(期):2024.46(8)
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