Effects of different vascular pathways on dialysis efficacy,microinflammatory status,and nutritional status in patients with chronic renal failure
Objective:To explore the hemodialysis efficacy of using a Tunneled Polyester Catheter(TCC)or Autologous Arteriovenous Fistula(AVF)vascular pathway in patients with chronic renal failure(CRF)and its impact on their nutritional and microinflammatory status.Methods:A total of 103 patients with CRF in our department from September 2021 to March 2023 were divided into two groups according to the way of vascular access.Fifty-one patients in the catheter group received TCC vascular access,and fifty-two patients in the internal fistula group received AVF vascular access.After 6 m dialysis,the levels of Interleukin-6(IL-6),hypersensitive C-reactive protein(hs-CRP),and tumor necrosis factor-α(TNF-α)were determined by Enzyme-linked immunosorbent assay(ELISA),serum albumin and hemoglobin were measured by the automatic biochemical analyzer,and the transferrin saturation level was calculated.The dialysis efficiency was evaluated based on the clearance rate and decreased rate of urea nitrogen,and the incidence of complications during the period was recorded.Results:The vascular pathway blood flow,urea nitrogen clearance rate,and urea nitrogen decrease rate in the fistula group were higher than those in the catheter group(P<0.05).After treatment,IL-6,hs-CRP,and TNF-α in the fistula group were significantly lower than in the catheter group,the transferrin saturation,serum ferritin,serum albumin,and hemoglobin levels were lower in the catheter group,and there were fewer complications in the fistula group(P<0.05).Conclusion:The dialysis efficiency of CRF patients using the AVF pathway is higher than that of the TCC pathway,and the effect of improving the patient's microinflammatory status,anemia,and nutritional status is significantly better than that of the TCC pathway,with fewer complications.
Chronic renal failureDialysis catheter with tunnel and polyester sleeveAutogenous arteriovenous fistulaDialysis efficiencyAnemia and nutritional statusMicroinflammatory state
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