Effect of non-invasive high-frequency ventilation on blood gas index and prognosis of neonatal respiratory distress syndrome
Objective:To investigate the effect of non-invasive high-frequency ventilation in the treatment of neonatal respiratory distress syndrome.Methods:A total of 106 children with respiratory distress syndrome admitted to our hospital from October 2020 to October 2023 were divided into two groups according to treatment methods.The control group received nasal continuous positive airway pressure(n=53),and the study group received non-invasive high-frequency oscillatory ventilation(n=53).Blood gas analysis indexes,pulmonary function indexes,apnea occurrence,non-invasive ventilation failure rate,and complications were compared between the two groups before and 72 hours after treatment.Results:After treatment,the oxygenation index(OI),arterial oxygen pressure(PaO2),and pH value of the study group in both groups significantly increased compared to pretreatment(P<0.05),and the study group was higher than the control group(P<0.05).However,the arterial carbon dioxide pressure(PaCO2)of both groups decreased compared to pretreatment,and the study group was lower than the control group(P<0.05).After treatment,the inhalation time(Ti),expiratory time(Te),and tidal volume(VT)of both groups obviously increased compared to pretreatment(P<0.05),and the study group was higher than the control group(P<0.05).The incidence of respiratory pauses and the failure rate of non-invasive ventilation in the study group were lower than those in the control group,and the disappearance time of respiratory pauses was shortened compared to the control group(P<0.05).Conclusion:Non-invasive high frequency ventilation can promote the improvement of blood gas analysis index and lung function index of children.
Non-invasive high frequency ventilationNewbornRespiratory distress syndromeBlood gas indexPrognosis