目的:探讨慢性精神分裂症经脑电生物反馈辅助治疗后的疗效及对认知、社会功能的影响.方法:选取2022年 1 月至 2023 年 9 月我院确诊并接受治疗的慢性精神分裂症患者 60 例为本次研究的对象,其中 30 例患者接受抗精神病药物治疗,归为对照组,另30例在抗精神病药物基础上进行脑电生物反馈疗法,归为观察组.比较两组的临床疗效(临床疗效总评量表-疾病严重程度(Clinical Global Impression-SI,CGI-SI))、脑电活动特征(异常不自主运动量表(Abnormal Involuntary Movement Scale,AIMS))、症状改善情况(现状精神病症状检查(Present State Examination,PSE))、生活质量(日常生活评定量表(Activity of Daily Living Scale,ADL))及社会功能(社会功能缺点挑选量表(Social Disability Screening Schedule,SDSS)).结果:治疗后两组CGI-SI评分、AIMS评分、PSE各维度评分、ADL评分及SDSS评分均显著改善(P＜0.05),且观察组各项评分均明显优于对照组(P＜0.05).结论:通过对比分析发现,脑电生物反馈疗法联合药物治疗后,患者临床表现、不自主运动症状及认知功能均可得到明显缓解,而且其生活能力及社会功能也得到不同程度的改善,可作为慢性精神分裂症的有效治疗方案.
Effect of electroencephalogram biofeedback assisted treatment on chronic schizophrenia
Objective:To investigate the therapeutic effect of electroencephalogram biofeedback assisted treatment on chronic schizophrenia and the impact on cognitive function and social function.Methods:Sixty patients with chronic schizophrenia diagnosed and treated at our hospital from January 2022 to September 2023 were selected as the study subjects.Among them,30 patients treated with antipsychotics were assigned to the control group.The other 30 patients received electroencephalogram biofeedback therapy on the basis of treatment of control group were assigned to the observation group.The therapeutic effect,brain electrical activities,symptom improvement,quality of life and social function in the two groups were compared through the Clinical Global Impression-SI(CGI-SI),Abnormal Involuntary Movement Scale(AIMS),Present State Examination(PSE),Activity of Daily Living Scale(ADL)and Social Disability Screening Schedule(SDSS),respectively.Results:After treatment,there were significant improvements in CGI-SI scores,AIMS scores,PSE scores,ADL scores and SDSS scores in both groups(P<0.05),and all scores of the observation group were significantly better than those of the control group(P<0.05).Conclusion:Clinical manifestations,involuntary motor symptoms and cognitive function in patients with chronic schizophrenia are significantly improved after electroencephalogram biofeedback therapy combined with drug therapy.In addition,the patients'activities of daily living and social function are improved to varying degrees.Therefore,the combined treatment can be used as an effective treatment for chronic schizophrenia.
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