Effects of compound α ketoacid tablets and Huangkui capsules on renal fibrosis and micro inflammation in patients with diabetes nephropathy
Objective:To study the effect of compound α ketoacid tablet combined with Huangkui capsule on renal fibrosis and micro inflammation in patients with diabetes nephropathy.Methods:From June 2022 to June 2023,70 patients with diabetes nephropathy in our hospital were selected as the study subjects.The patients were randomly divided into a control group and a combination group with 35 patients in each group.The control group received compound therapy α Ketone acid tablets,while combination group were treated with compound α Ketone acid tablets combined with Huangkui capsules.The clinical efficacy,renal fibrosis indicators,microinflammatory status indicators,blood sugar indicators,and adverse reactions were compared between the combination group and the control group before and after treatment.Results:After treatment,the clinical efficacy of the combination group was significantly better than that of the control group(P<0.05);After treatment,the levels of renal fibrosis indicators,microinflammatory status indicators and blood sugar indicators in two groups decreased,and the combined group had better indicators than the control group(P<0.05);No serious adverse reactions were observed during the 8-week course of treatment in both groups.Conclusion:The combination of Compound α ketoacid tablet and Huangkui capsule could slow down the progress of renal fibrosis,and improve the state of microinflammation in patients with diabetes nephropathy.
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