Efficacy of LEEP and CKC on cervical high-grade squamous intraepithelial lesion and observation of cervical regeneration status
Objective:To observe the difference in efficacy of loop electrosurgical excision procedure(LEEP)and cold knife conization(CKC)in the treatment of cervical high-grade squamous intraepithelial lesion(HSIL),and to compare the postoperative cervical regeneration status.Methods:Sixty patients with HSIL in the hospital were selected from January 2021 to June 2023 as the study subjects,and were divided into LEEP group and control group according to the envelope method,30 cases in each group.The LEEP group was treated with LEEP,while the control group was given CKC.The therapeutic effect,surgical indicators,cervical regeneration and complications were compared between groups.Results:After 6 months of treatment,the disease reversal rate in LEEP group was significantly lower than that in control group(P<0.05).The surgical time,intraoperative blood loss,and volume and length of conization tissue were significantly shorter or lower in LEEP group than those in control group(P<0.05).At 3 months and 6 months after surgery,the cervical volume and length in LEEP group were significantly more or longer than those in control group(P<0.05).There was no significant difference in the occurrence of complications between groups(P>0.05).Conclusion:CKC in the treatment of HSIL has a better effect than that of LEEP,but LEEP has simpler surgical operation,less bleeding and smaller damage to the cervix,and it is more conducive to postoperative cervical regeneration.
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