目的:对Web of science数据库收录的阿加曲班相关文献进行计量分析,探索的阿加曲班的科研力量分布、研究热点和发展趋势,为科研和临床合理用药提供参考.方法:利用 CiteSpace 软件分析 2001-2020 年 Web of science数据库收录的阿加曲班相关文献,并进行分析.结果:阿加曲班的主要发文地区为美国、日本、德国和加拿大.研究机构主要是美国和日本的大学及其附属医院.国内依达拉奉的研究机构主要是上海应用技术大学.阿加曲班抗凝对肝素诱导的血小板减少症的预防和治疗、阿加曲班的药效学和药物代谢动力学是阿加曲班的研究热点.结论:国内外阿加曲班的研究需要加强机构间的合作,促进作者间的沟通,国内学者应积极探索阿加曲班保护神经血管的机制和对肝素诱导的血小板减少症的治疗作用.
Bibliometric analysis of domestic and international Argatroban research literature based on CiteSpace
Objective:This study aims to conduct a bibliometric analysis of literature related to argatroban indexed in the Web of Science database,exploring the distribution of research strength,research hotspots,and development trends of argatroban,to provide references for scientific research and clinical rational drug use.Methods:CiteSpace software was used to analyze the literature on argatroban indexed in the Web of Science database from 2001 to 2020.Results:The primary regions for argatroban publications are the United States,Japan,Germany,and Canada.The main research institutions are universities and affiliated hospitals in the United States and Japan.In China,the leading research institution for edaravone,a related compound,is Shanghai Institute of Technology.Research hotspots for argatroban include its anticoagulant effects for the prevention and treatment of heparin-induced thrombocytopenia,as well as its pharmacodynamics and pharmacokinetics.Conclusion:Both domestic and international research on argatroban needs to strengthen collaboration between institutions and promote communication among authors.Chinese scholars should actively explore the mechanisms of argatroban in neurovascular protection and its therapeutic effects on ALS(Amyotrophic Lateral Sclerosis).
万方数据
维普
