Application of echocardiogram in evaluation of cardiac function impairment in patients with long-course T2DM
Objective:To explore the application value of echocardiogram in evaluating cardiac function impairment in patients with long-course type 2 diabetes mellitus(T2DM).Methods:A total of 90 patients with long-course T2DM in the hospital were enrolled between May 2021 and June 2023.According to presence or absence of cardiac function impairment,they were divided into concurrence group(n=42)and non-concurrence group(n=48).All patients underwent echocardiography.The echocardiogram parameters,clinical data and imaging indexes in the two groups were compared.The risk factors of cardiac function impairment were analyzed by Logistic regression analysis.The evaluation efficiency of echocardiogram parameters for cardiac function impairment was analyzed by receiver operating characteristic(ROC)curves.Results:There was no significant difference in gender,systolic blood pressure or diastolic blood pressure between non-concurrence group and concurrence group(P>0.05),but there were significant differences in age,fasting blood glucose,left atrial volume index(LAVI),ratio of early blood flow peak velocity to end-diastolic peak blood flow velocity(E/A),left ventricular ejection fraction(LVEF)and left ventricular global longitudinal strain(GLS)between the two groups(P<0.05).The results of Logistic regression analysis showed that increased LAVI,decreased LVEF and GLS were independent influencing factors of cardiac function impairment(P<0.05).The results of ROC curves analysis showed that area under the curve(AUC)and cut-off values of LAVI,LVEF and GLS for predicting cardiac function impairment were(0.781,0.676,0.796)and(30.302,63.514%,-15.452),showing general predictive value(P<0.05).Conclusion:The evaluation efficiency of echocardiogram is good for cardiac function impairment in patients with long-course T2DM.
EchocardiogramCardiac functionType 2 diabetes mellitusCourse of disease
万方数据
维普
