Infection and drug resistance characteristics of carbapenem-resistant Acinetobacter baumannii in ICU and general wards
Objective:To explore infection characteristics and drug resistance of carbapenem-resistant Acinetobacter baumannii(CRAB)in the intensive care unit(ICU)and general wards.Methods:A total of 120 patients with CRAB infection in the hospital were randomly enrolled between January 2022 and March 2024,including 60 cases in the ICU and 60 cases in general wards.The infection characteristics of CRAB in the two groups were observed by microbial identification and drug sensitivity analysis system,and drug resistance of CRAB was analyzed.Results:The main type of CRAB infection was respiratory tract infection in the ICU and general wards.In ICU and general wards,drug resistance rates of CRAB strains to tigecycline and minocycline were lower than those to the other antibiotics(P<0.05).The drug resistance rates of CRAB strains to ampicillin/sulbactam,cefoperazone/sulbactam,cefepime,and amikacin in the ICU were higher than those of in general wards(P<0.05).There was no significant difference in positive rates of drug resistance genes(AmpC,OXA-23,OXA-24,OXA-51,IMP-1,IMP-2,VIM-1,and VIM-2)between ICU and general wards(P>0.05).Conclusion:The main type of CRAB infection is respiratory tract infection in the ICU and general wards.Compared with general wards,drug resistance rates of CRAB strains are higher in ICU.
Intensive care unitGeneral wardAcinetobacter baumanniiCarbapenemDrug resistance
万方数据
维普
