Diagnostic value of ultrasonography of NT thickening and neck hydrocystoma in fetal heart malformation during early and middle pregnancy
Objective:To investigate the value of NT thickening combined with neck hygroma in the diagnosis of fetal heart malformation in early and middle pregnancy.Methods:A retrospective study was carried out on 129 cases of suspected fetal heart malformations who were screened during early and middle pregnancy from January 1,2019 to January 1,2023.The gold standard for the diagnosis of fetal heart malformations was taken by postpartum cardiac ultrasonography.All subjects underwent ultrasound examination,and compared the incidence of fetal heart malformation in different cervical hydras tumors and different NT thickening.To analyze the relationship between NT thickening,neck hydras tumor and fetal heart malformation and the diagnostic value of fetal heart malformation.Results:The results of gold standard examination showed that there were 31 cases of cardiac malformation,mainly with left heart dysplasia,accounting for 25.81%,followed by single atrium and single ventricle of main artery,constriction/rupture,accounting for 16.13%,and finally with persistent trunk artery and endocardial pad defect,accounting for 12.90%.The incidence of cardiac malformation in fetuses with NT thickness>4.5 mm was significantly higher than that in fetuses with NT thickness 2.5-4.5 mm(P<0.05).The rate of cardiac malformation in fetuses with cystic mass area>6.0 cm2 was significantly higher than that in fetuses with cystic mass area 3.0～6.0 cm2(P<0.05).Spearman correlation analysis showed that there was a positive correlation between NT thickening and neck hydrocystoma and fetal heart malformation(r=0.638,0.597,P<0.05).The diagnostic sensitivity of NT thickening combined with neck hycystoma was significantly higher than that of NT thickening combined with neck hycystoma alone(P<0.05),but there were no significant differences in specificity,accuracy,positive predictive value and negative predictive value among the three groups(P>0.05).Conclusion:There are many types of fetal heart malformations,mainly aortic coarctation/dissection and single atrium and single ventricle.Fetal heart malformation was positively correlated with NT thickening and neck hydsac tumor.The combined application of NT thickening and neck hydrocystoma can provide reference for early and middle stage diagnosis.
Early and middle pregnancyFetal heart malformationThickening of the transparent layer of neckHygroma of the neck
万方数据
维普
