Predictive analysis of blood uric acid and brain natriuretic peptide on the occurrence of atrial fibrillation after aortic valve replacement surgery
Objective:To analyze the predictive value of blood uric acid and brain natriuretic peptide(BNP)in the occurrence of atrial fibrillation after aortic valve replacement surgery.Method:117 patients who planned to undergo aortic valve replacement surgery at Nanyang Central Hospital from January 2020 to August 2023 were selected as the study subjects.The incidence of atrial fibrillation within 2 weeks after surgery was observed as the endpoint,and the patients were divided into occurrence and nonoccurrence groups.The general data and laboratory indexes of the two groups were collected and compared.The levels of blood uric acid and BNP were measured before operation,and the predictive value of blood uric acid and BNP levels on the occurrence of atrial fibrillation after aortic valve replacement was analyzed.Results:The left atrial volume,blood uric acid,and BNP levels in the occurrence group were higher than those in the non-occurrence group,with a statistical significant difference(P<0.05).The results of Logistic regression analysis showed that an increase in left atrial volume,blood uric acid,and BNP levels were risk factors for atrial fibrillation after aortic valve replacement surgery(OR>1,P<0.05).Receiver operating characteristic curve(ROC)was drawn,and the results showed that the area under the curve(AUC)of blood uric acid,BNP and the combination for predicting the occurrence of atrial fibrillation after aortic valve replacement were all greater than 0.7,which showed good predictive value,and the combination had the best predictive performance.Conclusion:Abnormally high levels of uric acid and BNP may increase the risk of atrial fibrillation after aortic valve replacement,and the combined detection of these two indicators may improve the predictive value of postoperative atrial fibrillation.
万方数据
维普
