Effect of flunarizine hydrochloride assisted Nimodipine in the treatment of vascular dementia
Objective:To investigate the effect of flunarizine hydrochloride assisted nimodipine in the treatment of vascular dementia.Methods:72 patients with vascular dementia admitted to our hospital from October 2020 to January 2023 were selected as the study objects.The patients were randomly divided into control group and observation group,36 cases in each group.The control group was treated with nimodipine.Observation group was treated with flunarizine hydrochloride combined with nimodipine.The therapeutic effect of the two groups was compared after 2 months of treatment.Before and after treatment,dementia degree was assessed by clinical dementia rating scale and daily living ability was assessed by modified Barthel index.Results:After treatment,the total effective rate of observation group was significantly higher than that of control group(P<0.05).Compared with before treatment,the clinical dementia assessment scale scores were significantly reduced in both groups,with the observation group being more significant(P<0.05).Compared with before treatment,the modified Barthel index scores in both groups were significantly improved,with the observation group being more significant(P<0.05).Conclusion:Flunarizine hydrochloride assisted nimodipine is effective in the treatment of vascular dementia,which can reduce the degree of dementia and improve the ability of daily living.
Vascular dementiaFlunarizine hydrochlorideNimodipineDegree of dementiaAbility of daily living
万方数据
维普
