Application of endoscopic titanium clip hemostasis combined with esomeprazole in the treatment of acute upper gastrointestinal bleeding
Objective:To explore the efficacy of esomeprazole assisted endoscopic titanium clip hemostasis in the treatment of acute upper gastrointestinal bleeding,and analyze its safety.Method:A retrospective analysis was conducted on the clinical data of 86 patients with acute upper gastrointestinal bleeding admitted to Xinyang Central Hospital from July 2022 to October 2023.They were divided into a control group(42 cases)and an observation group(44 cases)based on different treatment methods,using titanium clips under endoscopy for hemostasis.The re bleeding situation,clinical indicators(blood transfusion volume during treatment,hospital stay),and incidence of postoperative adverse reactions were compared between the two groups 3 and 5 days after the first endoscopic titanium clip hemostasis treatment.Result:The rate of rebleeding in the observation group after 3 days of treatment was significantly lower than that in the control group(P<0.05).The rate of rebleeding after 5 days of treatment in both groups decreased,and the observation group was lower than the control group,but the difference was not statistically significant(P>0.05).The blood transfusion volume of the observation group was significantly lower than that of the control group,and the hospitalization time was significantly shorter than that of the control group(P<0.05).The incidence of adverse reactions between the two groups was not significantly different(P>0.05).Conclusion:Endoscopic titanium clip hemostasis combined with esomeprazole in the treatment of acute upper gastrointestinal bleeding can reduce the rate of rebleeding,reduce blood transfusion volume,promote patient recovery,and have high safety.
万方数据
维普
