Application value of combined detection of cTnI,CK-MB and Myo in the diagnosis of early acute myocardial infarction
Objective:To investigate the diagnostic value of cardiac troponin(cTnI),creatine kinase isoenzymes(CK-MB)and Myoglobin(Myo)on early Acute myocardial infarction(AMI).Methods:From January 2020 to January 2023,60 patients with early AMI symptoms and diagnosed AMI were selected as the myocardial infarction group.At the same time,60 healthy subjects who underwent physical examination in our hospital during the same period were selected as the control group.Baseline data were collected for both groups.Serum levels of cTnI,CK-MB and Myo were detected in the two groups.Baseline data and cTnI,CK-MB and Myo levels of the two groups were analyzed and compared.Receiver operating characteristic(ROC)curve was drawn to evaluate the diagnostic value of cTnI,CK-MB and Myo combined detection in early AMI.Results:There was no significant difference in baseline data between the two groups(P>0.05).The levels of cTnI,CK-MB and Myo in MI group were significantly higher than those in control group(P<0.05).The area under the curve(AUC)of cTnI,CK-MB,Myo alone and combined diagnosis of early AMI were 0.845,0.776,0.785,0.929,respectively.The value of combined diagnosis was better(Z1=1.987,P1=0.044,Z2=3.195,P2=0.001,Z3=2.983,P3=0.003).Conclusion:The combined detection of cTnI,CK-MB and Myo can improve the detection rate of early AMI.
Acute myocardial infarctionTroponinCreatine kinase isoenzymeMyoglobinDiagnostic value
万方数据
维普
