Changes and clinical significance of myocardial enzymes and apoB/apoA-1 ratio in patients with atherosclerosis
Objective:To explore the changes and clinical significance of myocardial enzymes and apolipoprotein B/apolipoprotein A-1(apoB/apoA-1)ratio in patients with atherosclerosis.Methods:From January 2022 to March 2024,60 patients with atherosclerosis treated in the hospital were enrolled as the research objects.According to presence or absence of myocardial infarction,they were divided into myocardial infarction group and non-myocardial infarction group.Basic data,myocardial enzymes and apoB/apoA-1 ratios of the two groups were compared.The relationship between myocardial enzymes,apoB/apoA-1 ratio and the occurrence of myocardial infarction was discussed.ROC curves were used to analyze the predictive value of the two groups for the occurrence of myocardial infarction.Results:The incidence of myocardial infarction in this study was 45.00%(27/60).The proportion of patients aged 60 or older,the levels of LDLC,TC,TG and myocardial enzymes,and apoB/apoA-1 ratio in the myocardial infarction group were significantly higher than those in the non-myocardial infarction group(P<0.05).After adjusting confounders,it was found that AST,LDH,CK,CK-MB and apoB/apoA-1 ratio were independent risk factors for myocardial infarction in patients with atherosclerosis(P<0.05).ROC curves indicated that the predictive value of myocardial enzymes combined with apoB/apoA-1 ratio for the occurrence of myocardial infarction in patients with atherosclerosis was high.The AUC,sensitivity and specificity were 0.823,74.10%and 91.20%.Conclusion:Myocardial enzymes and apoB/apoA-1 ratio in patients with myocardial infarction caused by atherosclerosis are significantly increased.Combined detection of the two is helpful for predicting the occurrence of myocardial infarction.
万方数据
维普
