Value of prenatal two-dimensional ultrasonography combined with four-dimensional ultrasonography in the clinical diagnosis of fetal heart malformations
Objective:To analyze the diagnostic efficacy of two-dimensional and four-dimensional color ultrasound in screening fetal heart malformations,and analyze the value of the combined diagnosis of the above two methods in order to improve the diagnostic efficacy of fetal heart malformations.Methods:Clinical data of 500 pregnant women admitted from January 2019 to January 2021 were retrospectively analyzed.All subjects were screened by 2D ultrasound and 4D ultrasound,and the results of induction of labor or postpartum follow-up were used as the gold standard.The consistency of two dimensional ultrasound and four dimensional ultrasound with gold standard was analyzed.Results:There were 52 cases(10.40%)of cardiac malformations in 500 pregnant women after induction of labor and postpartum follow-up.The results of two-dimensional ultrasound examination showed that the sensitivity was 57.69%,specificity 98.21%,positive predictive value was 78.95%,negative predictive value was 95.24%,and the accuracy was 94.00%.The Kappa value of two-dimensional ultrasound examination and gold standard was 0.635.The results of 4D ultrasound showed that the sensitivity was 63.46%,the specificity was 98.44%,the positive predictive value was 82.50%,the negative predictive value was 95.87%,and the accuracy rate was 94.80%.The Kappa value of 4D ultrasound and gold standard was 0.689.The results of 2D ultrasound combined with 4D ultrasound showed that the sensitivity was 92.31%,the specificity was 99.55%,the positive predictive value was 96.00%,the negative predictive value was 99.11%,and the accuracy was 98.80%.The Kappa value of the combined diagnosis and the gold standard was 0.934.Conclusion:The combined application of 2D color ultrasound and 4D ultrasound in the screening of fetal heart malformation can significantly improve the diagnostic efficiency and reduce the risk of missed diagnosis and misdiagnosis.
FetusHeart malformationTwo-dimensional color ultrasoundFour dimensional color ultrasoundUniteDiagnostic efficiency