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四维超声成像联合NT检查在胎儿体表畸形筛查中的应用

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目的:探析四维超声成像联合颈项透明层厚度(Nuchal translucency,NT)检查在胎儿体表畸形筛查中的应用价值.方法:选取 2020 年 1 月至 2023 年 2 月期间于本院产检的 554 例孕妇作为研究对象.所有孕妇均行NT检查和四维超声成像检查,对孕妇进行随访.将引产或产后结果作为金标准,统计NT检查、四维超声成像检查单独及联合检出率,并分析单一NT检查、单一四维超声成像检查以及联合检查诊断胎儿体表缺陷的诊断效能.结果:本研究随访至引产或产后,554例孕妇中有11例胎儿出现体表畸形,胎儿体表畸形发生率为1.99%(11/554),其中四肢畸形胎儿占比 54.55%(6/11),唇腭裂胎儿占比 36.36%(4/11),脐膨出胎儿占比 9.09%(1/11);以引产与产后随访结果为"金标准",NT单一检查的检出率为 63.64%(7/11),四维超声成像单一检查的检出率为 72.73%(8/11),NT联合四维超声成像检查的检出率为100.00%(11/11);联合检查胎儿体表畸形的准确度最高(P<0.05);联合检查评估胎儿体表畸形结果与"金标准"的一致性强(Kappa 值=0.915,P<0.001).结论:胎儿体表畸形可采用四维超声成像与NT检查诊断,二者联合诊断可提高诊断准确度与灵敏度,联合诊断更具价值.
Application of four-dimensional ultrasound imaging combined with NT examination in screening for fetal surface deformities
Objective:To explore the application value of four-dimensional ultrasound imaging combined with nuchal translucency(NT)examination in screening fetal surface deformities.Methods:554 pregnant women who underwent prenatal examinations in our hospital from January 2020 to February 2023 were selected as the study subjects.All pregnant women underwent NT examination and four-dimensional ultrasound imaging,and were followed up.Labor induction or postnatal results were used as the gold standard,the detection rates of NT examination and 4D ultrasound imaging alone and combined were counted,and the diagnostic efficacy of single NT examination,4D ultrasound imaging examination and combined examination in diagnosing fetal body surface defects was analyzed.Results:In this study,11 out of 554 pregnant women were followed up to induced labor or postpartum,and the incidence of fetal surface abnormalities was 1.99%(11/554).Among them,54.55%(6/11)were deformed limbs,36.36%(4/11)were cleft lip and palate,and 9.09%(1/11)were omphalocele.Labor induction and postpartum follow-up were taken as the"gold standard",the detection rate of NT single examination was 63.64%(7/11),the detection rate of 4D ultrasound imaging single examination was 72.73%(8/11),and the detection rate of NT combined 4D ultrasound imaging was 100.00%(11/11).The accuracy of joint examination for fetal surface deformities was the highest(P<0.05).The results of combined examination in evaluating fetal surface malformations were in good agreement with the"gold standard"(Kappa value=0.915,P<0.001).Conclusion:Fetal surface deformities can be diagnosed using four-dimensional ultrasound imaging and NT examination,but the combined diagnosis of the two can improve diagnostic accuracy and sensitivity,and the combined diagnosis is more valuable.

Fetal surface deformitiesFour-dimensional ultrasound imagingNuchal translucencyDiagnostic value

王洪瑞

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郑州市中医院彩超室,河南 郑州 450000

胎儿体表畸形 四维超声成像 颈项透明层厚度 诊断价值

2024

四川生理科学杂志
四川省生理科学会

四川生理科学杂志

影响因子:0.575
ISSN:1671-3885
年,卷(期):2024.46(10)