Application of four-dimensional ultrasound imaging combined with NT examination in screening for fetal surface deformities
Objective:To explore the application value of four-dimensional ultrasound imaging combined with nuchal translucency(NT)examination in screening fetal surface deformities.Methods:554 pregnant women who underwent prenatal examinations in our hospital from January 2020 to February 2023 were selected as the study subjects.All pregnant women underwent NT examination and four-dimensional ultrasound imaging,and were followed up.Labor induction or postnatal results were used as the gold standard,the detection rates of NT examination and 4D ultrasound imaging alone and combined were counted,and the diagnostic efficacy of single NT examination,4D ultrasound imaging examination and combined examination in diagnosing fetal body surface defects was analyzed.Results:In this study,11 out of 554 pregnant women were followed up to induced labor or postpartum,and the incidence of fetal surface abnormalities was 1.99%(11/554).Among them,54.55%(6/11)were deformed limbs,36.36%(4/11)were cleft lip and palate,and 9.09%(1/11)were omphalocele.Labor induction and postpartum follow-up were taken as the"gold standard",the detection rate of NT single examination was 63.64%(7/11),the detection rate of 4D ultrasound imaging single examination was 72.73%(8/11),and the detection rate of NT combined 4D ultrasound imaging was 100.00%(11/11).The accuracy of joint examination for fetal surface deformities was the highest(P<0.05).The results of combined examination in evaluating fetal surface malformations were in good agreement with the"gold standard"(Kappa value=0.915,P<0.001).Conclusion:Fetal surface deformities can be diagnosed using four-dimensional ultrasound imaging and NT examination,but the combined diagnosis of the two can improve diagnostic accuracy and sensitivity,and the combined diagnosis is more valuable.
Fetal surface deformitiesFour-dimensional ultrasound imagingNuchal translucencyDiagnostic value