Effect of phacoemulsification combined with lower pupil angle separation in the treatment of APACG patients with age-related cataracts and its influence on the loss of corneal endothelial cells
Objective:To explore the effects of phacoemulsification(PE)combined with goniosynechialysis(GSL)on patients with acute primary angle closure glaucoma(APACG)and age-related cataracts.Methods:A total of 115 patients with APACG combined with age-related cataracts were selected from our department from August 2021 to June 2023 and divided into two groups according to the lottery method.Fifty-seven cases in the control group were treated with PE combined with trabeculectomy(TE),while fifty-eight cases in the observation group were treated with PE combined with GSL.Intraocular pressure(IOP)was measured using a non-contact tonometer before surgery,1 week after surgery,4 weeks after surgery,and 12 weeks after surgery.The patient's best corrected visual acuity(BCVA)was measured using a TX-20 tonometer;the anterior chamber angle was measured using ultrasound biomicroscopy before and 12 weeks after surgery,the corneal endothelial cell loss(ECL)was measured using a corneal endothelial cell density instrument,and the patient's surgical complications were recorded.Results:The IOP level in the observation group was higher than that in the control group at 1 week and 4 weeks after surgery,the anterior chamber angle in the observation group was higher than that in the control group at 12 weeks after surgery,and complication rate and ECL were lower than that in the control group,the difference was statistically significant(P<0.05).Conclusion:PE combined with GSL can effectively improve the best corrected visual acuity,IOP,anterior chamber Angle,and ECL in APACG patients with cataracts,and it is safe.
万方数据
维普
