Diagnostic effect of 18F-FDG PET/CT combined with HRCT on primary lung cancer
Objective:Analysis of 18 fluoro-deoxyglucose(18F-2-deoxy-2-fluoro-D-glucose),18F-FDG Positron Emission Tomography(PET/CT)combined with High resolution CT(High resolution CT)The diagnostic effect of HRCT in primary lung cancer.Methods:A total of 122 patients with pulmonary space-occupying lesions admitted to our hospital from May 2020 to October 2023 were selected as the research objects.The results of pathological examination are the gold standard for the diagnosis of primary lung cancer.All patients underwent 18F-FDG PET/CT and HRCT tests.The detection rate of 18F-FDG PET/CT and HRCT for primary lung cancer was calculated and compared.To analyze the diagnostic efficacy of 18F-FDG PET/CT and HRCT alone and in combination in the diagnosis of primary lung cancer.Results:The results of pathological examination showed that 91 of the 122 patients were diagnosed as primary lung cancer and 31 were benign lung lesions.18F-FDG PET/CT diagnosis showed 76 cases of primary malignant lesions,and HRCT scan showed 73 cases of primary malignant lesions.The sensitivity of 18F-FDG PET/CT in the diagnosis of primary lung cancer was 82.89%(63/76),the specificity was 39.13%(18/46),the positive predictive value was 69.23%(63/91)and the negative predictive value was 58.06%(18/31).The sensitivity of HRCT in the diagnosis of primary lung cancer was 79.45%(58/73),the specificity was 32.65%(16/49),the positive predictive value was 63.73%(58/91)and the negative predictive value was 51.61%(16/31).The sensitivity of 18F-FDG PET/CT combined with HRCT was 89.41%(76/85),the specificity was 59.45%(22/37),the positive predictive value was 83.52%(76/91),and the negative predictive value was 70.97%(22/31).The sensitivity and specificity of combined diagnosis were significantly higher than those of single diagnosis(P<0.05).The SUVmax value and the proportion of SUVmax≥2.5 in primary lung cancer were significantly higher than those in benign lung lesions(P<0.05).Conclusion:The combined examination of 18F-FDG PET/CT and HRCT can improve the sensitivity and specificity of the diagnosis of primary lung cancer.
18F-FDG PET/CTJoint detectionHRCTPrimary lung cancer
万方数据
维普
