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胸部CT联合实验室指标在儿童肺炎支原体肺炎诊断中的价值

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目的:探讨胸部CT联合实验室指标对儿童肺炎支原体肺炎(Mycoplasma pneumoniae pneumonia,MPP)的诊断价值.方法:选取 2022 年 2 月至 2024 年 2 月我院收治的 66 例肺炎患儿作为研究对象,根据肺炎支原体(Mycoplasma pneumoniae,MP)抗体Ig M检查结果分为MMP组(n=36)和非MPP组(n=30).两组均行胸部CT检查,并采集空腹静脉血静脉血,测定血清白细胞计数(White blood cell count,WBC)、C反应蛋白(C-reactive protein,CRP)、降钙素原(Procalcitonin,PCT)及D-二聚体(D-dimer,D-D)水平,比较两组上述血清实验室指标差异,绘制受试者工作特征(Receiver operating characteristic,ROC)评估胸部CT联合实验室指标对儿童MPP的诊断价值.结果:本次研究入组的 66 例肺炎患儿中,36例经MP抗体Ig M检查明确诊断为MPP,胸部CT诊断儿童MPP的准确率为 74.24%;MPP组支气管壁增厚的检出率、磨玻璃影检出率、网状影检出率均明显高于非MPP组(P<0.05);MPP组血清WBC、CRP、PCT及D-D水平均明显低于非MPP组(P<0.05);五项联合诊断儿童MPP的曲线下面积(Area under curve,AUC)明显高于各项单独诊断(P<0.05).结论:胸部CT检查及血清WBC、CRP、PCT、D-D测定对儿童MPP的鉴别诊断有一定价值,且其联合可提高诊断效能.
Value of chest CT combined with laboratory indicators in the diagnosis of Mycoplasma pneumoniae pneumonia in children
Objective:To investigate the diagnostic value of chest CT combined with laboratory indicators for Mycoplasma pneumoniae pneumonia(MPP)in children.Methods:From February 2022 to February 2024,66 children with pneumonia admitted to our hospital were selected as the study subjects.According to the test results of Mycoplasma pneumoniae(MP)antibody(IgM),the subjects were divided into MMP group(n=36)and non-MMP group(n=30).Both groups underwent chest CT examination.Fasting venous blood was collected to measure serum white blood cell count(WBC),C-reactive protein(CRP),procalcitonin(PCT)and D-dimer(D-D)levels.The differences in above serum laboratory indicators between the two groups were analyzed.The receiver operating characteristic(ROC)curves were plotted to evaluate the diagnostic value of chest CT combined with laboratory indicators for MPP in children.Results:Among the 66 children with pneumonia,36 cases were diagnosed with MPP through MP antibody IgM test.The accuracy of chest CT for diagnosing MPP in children was 74.24%.The detection rates of bronchial wall thickening,ground glass opacities,and reticular opacities in the MPP group were significantly higher than those in the non MPP group(P<0.05).Serum WBC,CRP,PCT and D-D levels in the MPP group were significantly lower than those in the non-MPP group(P<0.05).The area under curve(AUC)of joint diagnosis with the five was 0.902,higher than that of individual diagnosis(P<0.05).Conclusion:Chest CT and serum WBC,CRP,PCT and D-D all are helpful for diagnosing MPP in children,and their combination can improve diagnostic efficacy.

ChildrenMycoplasma pneumoniae pneumoniaChest CTLaboratory indicators

兰亮、文雅、谭维

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芦溪县人民医院放射科,江西 萍乡 337200

儿童 肺炎支原体肺炎 胸部CT 实验室指标

2024

四川生理科学杂志
四川省生理科学会

四川生理科学杂志

影响因子:0.575
ISSN:1671-3885
年,卷(期):2024.46(10)